Nucleotide carrier mixture with transport selectivity for ribonucleoside-5'-phosphates

被引:40
作者
Riggs, JA
Hossler, KA
Smith, BD
Karpa, MJ
Griffin, G
Duggan, PJ
机构
[1] UNIV NOTRE DAME,DEPT CHEM & BIOCHEM,NOTRE DAME,IN 46556
[2] JAMES COOK UNIV N QUEENSLAND,SCH MOL SCI,DEPT CHEM & CHEM ENGN,TOWNSVILLE,QLD 4811,AUSTRALIA
基金
美国国家科学基金会; 澳大利亚研究理事会;
关键词
D O I
10.1016/0040-4039(96)01385-8
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A carrier mixture of lipophilic boronic acid and bis(quaternary ammonium cation) greatly facilitates the transport of ribonucleoside monophosphates through liquid organic membranes, at neutral pH. Transport selectivity was determined for the isomers of GMP. The observed order of noncompetitive transport rates war 5'-GMP > 2'-GMP > 3'-GMP. Copyright (C) 1996 Elsevier Science Ltd
引用
收藏
页码:6303 / 6306
页数:4
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