Lasting improvement of hyperglycaemia and bodyweight:: Low-carbohydrate diet in type 2 diabetes.: A brief report

被引:14
作者
Nielsen, JV [1 ]
Jönsson, E [1 ]
Nilsson, AK [1 ]
机构
[1] Blekingesjukhuset, Dept Med, S-37441 Karlshamn, Sweden
关键词
D O I
10.3109/2000-1967-182
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In two groups of obese patients with type 2 diabetes the effects of 2 different diet compositions were tested with regard to glycaemic control and bodyweight. A group of 16 obese patients with type 2 diabetes was advised on a low-carbohydrate diet, 1800 kcal for men and 1600 kcal for women, distributed as 20 % carbohydrates, 30 % protein and 50 % fat. Fifteen obese diabetes patients on a high-carbohydrate diet were control group. Their diet, 1600-1800 kcal for men and 1400-1600 kcal for women, consisted of approximately 60 % carbohydrates, 15 % protein and 25 % fat. Positive effects on the glucose levels were seen very soon. After 6 months a marked reduction in bodyweight of patients in the low-carbohydrate diet group was observed, and this remained one year later. After 6 months the mean changes in the low-carbohydrate group and the control group respectively were (+/- SD): fasting blood glucose (f-BG): -3.4 +/- 2.9 and -0.6 +/- 2.9 mmol/l; HBA 1 c: -1.4 +/- 1.1 % and -0.6 +/- 1.4 %; Body Weight: -11.4 +/- 4 kg and -1.8 +/- 3.8 kg; BMI: -4.1 +/- 1.3 kg/m and -0.7 +/- 1.3 kg/m_. Large changes in blood glucose levels were seen immediately. Conclusion: A low-carbohydrate diet is an effective tool in the treatment of obese patients with type 2 diabetes.
引用
收藏
页码:69 / 73
页数:5
相关论文
共 14 条
[1]   A randomized trial comparing a very low carbohydrate diet and a calorie-restricted low fat diet on body weight and cardiovascular risk factors in healthy women [J].
Brehm, BJ ;
Seeley, RJ ;
Daniels, SR ;
D'Alessio, DA .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2003, 88 (04) :1617-1623
[2]   Metabolic Syndrome and Low-Carbohydrate Ketogenic Diets in the Medical School Biochemistry Curriculum [J].
Feinman, Richard D. ;
Makowske, Mary .
METABOLIC SYNDROME AND RELATED DISORDERS, 2003, 1 (03) :189-197
[3]   Thermodynamics and Metabolic Advantage of Weight Loss Diets [J].
Feinman, Richard D. ;
Fine, Eugene J. .
METABOLIC SYNDROME AND RELATED DISORDERS, 2003, 1 (03) :209-219
[4]   A randomized trial of a low-carbohydrate diet for obesity [J].
Foster, GD ;
Wyatt, HR ;
Hill, JO ;
McGuckin, BG ;
Brill, C ;
Mohammed, BS ;
Szapary, PO ;
Rader, DJ ;
Edman, JS ;
Klein, S .
NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (21) :2082-2090
[5]   An increase in dietary protein improves the blood glucose response in persons with type 2 diabetes [J].
Gannon, MC ;
Nuttall, FQ ;
Saeed, A ;
Jordan, K ;
Hoover, H .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2003, 78 (04) :734-741
[6]   Utility of a short-term 25% carbohydrate diet on improving glycemic control in type 2 diabetes mellitus [J].
Gutierrez, M ;
Akhavan, M ;
Jovanovic, L ;
Peterson, CM .
JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION, 1998, 17 (06) :595-600
[7]  
OBRIEN KD, 2003, GREATER REDUCITON IN
[8]   A low-carbohydrate as compared with a low-fat diet in severe obesity [J].
Samaha, FF ;
Iqbal, N ;
Seshadri, P ;
Chicano, KL ;
Daily, DA ;
McGrory, J ;
Williams, T ;
Williams, M ;
Gracely, EJ ;
Stern, L .
NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (21) :2074-2081
[9]   Effects of a low-carbohydrate diet on weight loss and cardiovascular risk factors in overweight adolescents [J].
Sondike, SB ;
Copperman, N ;
Jacobson, MS .
JOURNAL OF PEDIATRICS, 2003, 142 (03) :253-258
[10]   Clinical Experience of a Carbohydrate-Restricted Diet: Effect on Diabetes Mellitus [J].
Vernon, Mary C. ;
Mavropoulos, John ;
Transue, Melissa ;
Yancy, William S., Jr. ;
Westman, Eric C. .
METABOLIC SYNDROME AND RELATED DISORDERS, 2003, 1 (03) :233-237