Stimulus features affecting psychophysical detection thresholds for electrical stimulation of the cochlea .3. Pulse polarity

被引:16
作者
Coste, RL [1 ]
Pfingst, BE [1 ]
机构
[1] UNIV MICHIGAN,MED CTR,KRESGE HEARING RES INST,DEPT OTOLARYNGOL,ANN ARBOR,MI 48109
关键词
D O I
10.1121/1.414796
中图分类号
O42 [声学];
学科分类号
070206 ; 082403 ;
摘要
Effects of initial-phase polarity on psychophysical detection thresholds for electrical stimulation of the cochlea were examined in four nonhuman primates using trains of biphasic and triphasic charge-balanced pulses. Initial-phase polarity had small but consistent effects on the levels and slopes of threshold versus phase duration functions. These effects were consistent with the hypothesis that the initial-phase polarity affects the site of action potential initiation. Thresholds for biphasic pulses were lower than those for triphasic pulses, suggesting that the system is responsive to both positive and negative phases of the stimulus. Interactions between initial-phase polarity, pulse waveform, and phase duration were observed. (C) 1996 Acoustical Society of America.
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收藏
页码:3099 / 3108
页数:10
相关论文
共 13 条
[1]   ACTION POTENTIAL IN MYELINATED NERVE FIBRE OF XENOPUS LAEVIS AS COMPUTED ON BASIS OF VOLTAGE CLAMP DATA [J].
FRANKENHAEUSER, B ;
HUXLEY, AF .
JOURNAL OF PHYSIOLOGY-LONDON, 1964, 171 (02) :302-&
[2]   POLARITY ORDER OF BIPHASIC SQUARE PULSE ELECTRIC-CURRENT STIMULATION OF HUMAN COCHLEAR NERVE - OBSERVATIONS WITH TRANSTYMPANIC ELECTRODES [J].
GAME, CJA ;
THOMSON, DR ;
GIBSON, WPR ;
PAUKA, CK .
JOURNAL OF THE NEUROLOGICAL SCIENCES, 1989, 90 (03) :291-298
[3]   The strength-duration relation for electric excitation of medullated nerve [J].
Hill, AV .
PROCEEDINGS OF THE ROYAL SOCIETY SERIES B-BIOLOGICAL SCIENCES, 1936, 119 (815) :440-453
[4]  
*I LAB AN RES, 1985, NAT I HLTH PUBL, V8523
[5]   Functional responses from guinea pigs with cochlear implants .1. Electrophysiological and psychophysical measures [J].
Miller, CA ;
Woodruff, KE ;
Pfingst, BE .
HEARING RESEARCH, 1995, 92 (1-2) :85-99
[6]   EFFECTS OF PHASE DURATION ON DETECTION OF ELECTRICAL-STIMULATION OF THE HUMAN COCHLEA [J].
MOON, AK ;
ZWOLAN, TA ;
PFINGST, BE .
HEARING RESEARCH, 1993, 67 (1-2) :166-178
[7]   TEMPORAL RESPONSE PATTERNS OF AUDITORY-NERVE FIBERS TO ELECTRICAL-STIMULATION IN DEAFENED SQUIRREL-MONKEYS [J].
PARKINS, CW .
HEARING RESEARCH, 1989, 41 (2-3) :137-168
[8]   STIMULUS FEATURES AFFECTING PSYCHOPHYSICAL DETECTION THRESHOLDS FOR ELECTRICAL-STIMULATION OF THE COCHLEA .1. PHASE DURATION AND STIMULUS-DURATION [J].
PFINGST, BE ;
DEHAAN, DR ;
HOLLOWAY, LA .
JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA, 1991, 90 (04) :1857-1866
[9]   CHRONIC SKULL-ANCHORED PERCUTANEOUS IMPLANTS IN NON-HUMAN PRIMATES [J].
PFINGST, BE ;
ALBREKTSSON, T ;
TJELLSTROM, A ;
MILLER, JM ;
ZAPPIA, J ;
XUE, XL ;
WEISER, F .
JOURNAL OF NEUROSCIENCE METHODS, 1989, 29 (03) :207-216
[10]   STIMULUS FEATURES AFFECTING PSYCHOPHYSICAL DETECTION THRESHOLDS FOR ELECTRICAL-STIMULATION OF THE COCHLEA .2. FREQUENCY AND INTERPULSE INTERVAL [J].
PFINGST, BE ;
MORRIS, DJ .
JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA, 1993, 94 (03) :1287-1294