Stem cells for regenerative medicine - Biological attributes and clinical application

被引:20
作者
Gordon, Myrtle Y. [1 ]
机构
[1] Univ London Imperial Coll Sci Technol & Med, Dept Haematol, Fac Med, London W12 0NN, England
关键词
D O I
10.1016/j.exphem.2008.01.013
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The place of stem cells in the therapeutic armamentarium is currently subject to intense scrutiny. One issue is the nature of the stem cells themselves, and their relationship to better-known stem cells, such as hematopoietic stem cells. Here it is argued that the stem cells we propose for therapeutic application may be more closely related to embryonic cells than are hematopoietic stem cells. A second issue is how the stem cells may best be manipulated for therapeutic use; this includes stem cell purification, amplification, fate selection, and suitability for clinical use. (C) 2008 ISEH - Society for Hematology and Stem Cells. Published by Elsevier Inc.
引用
收藏
页码:726 / 732
页数:7
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