Comparative nucleotide sequence analysis of polymorphic variable-number tandem-repeat loci in Mycobacterium ulcerans

被引：19

作者：

Ablordey, A

Hilty, M

Stragier, P

Swings, J

Portaels, F ^{[1
]}

机构：

[1] Inst Trop Med Prince Leopold, Mycobacteriol Unit, B-2000 Antwerp, Belgium

[2] Swiss Trop Inst, CH-4002 Basel, Switzerland

[3] State Univ Ghent, Microbiol Lab, B-9000 Ghent, Belgium

[4] State Univ Ghent, BCCM LMG Culture Collect, B-9000 Ghent, Belgium

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2005年 / 43卷 / 10期

关键词：

D O I：

10.1128/JCM.43.10.5281-5284.2005

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We analyzed a set of variable-number tandem-repeat (VNTR) loci to assess their nucleotide sequence diversity in isolates of three Mycobacterium ulcerans genotypes. Sequence variants in two loci resulted in intraspecies resolution of Southeast Asian and Asian genotypes in contrast to a homogenous sequence composition among African isolates. Nucleotide sequence polymorphism in repeat units can enhance discrimination of VNTR loci.

引用

页码：5281 / 5284

页数：4

共 18 条

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