Cerebral blood flow measurements by magnetic resonance imaging bolus tracking:: Comparison with [15O]H2O positron emission tomography in humans

被引:169
作者
Ostergaard, L
Johannsen, P
Host-Poulsen, P
Vestergaard-Poulsen, P
Asboe, H
Gee, AD
Hansen, SB
Cold, GE
Gjedde, A
Gyldensted, C
机构
[1] Aarhus Kommune Hosp, Dept Neuroradiol, DK-8000 Aarhus, Denmark
[2] Aarhus Kommune Hosp, Dept Biomed Engn, DK-8000 Aarhus, Denmark
[3] Aarhus Kommune Hosp, Dept Neurosurg, DK-8000 Aarhus, Denmark
[4] Aarhus Kommune Hosp, Dept Neuroanesthesiol, DK-8000 Aarhus, Denmark
[5] Aarhus Kommune Hosp, PET Ctr, DK-8000 Aarhus, Denmark
关键词
cerebral blood flow; dynamic magnetic resonance imaging; humans; susceptibility contrast;
D O I
10.1097/00004647-199809000-00002
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In six young, healthy volunteers, a novel method to determine cerebral blood flow (CBF) using magnetic resonance (MR) bolus tracking was compared with [O-15]H2O positron emission tomography (PET). The method yielded parametric CBF images with tissue contrast in good agreement with parametric PET CBF images. Introducing a common conversion factor, MR CBF values could be converted into absolute flow rates, allowing comparison of CBF values among normal subjects.
引用
收藏
页码:935 / 940
页数:6
相关论文
共 14 条
  • [1] AUTOMATIC 3D INTERSUBJECT REGISTRATION OF MR VOLUMETRIC DATA IN STANDARDIZED TALAIRACH SPACE
    COLLINS, DL
    NEELIN, P
    PETERS, TM
    EVANS, AC
    [J]. JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 1994, 18 (02) : 192 - 205
  • [2] MR CONTRAST DUE TO MICROSCOPICALLY HETEROGENEOUS MAGNETIC-SUSCEPTIBILITY - NUMERICAL SIMULATIONS AND APPLICATIONS TO CEREBRAL PHYSIOLOGY
    FISEL, CR
    ACKERMAN, JL
    BUXTON, RB
    GARRIDO, L
    BELLIVEAU, JW
    ROSEN, BR
    BRADY, TJ
    [J]. MAGNETIC RESONANCE IN MEDICINE, 1991, 17 (02) : 336 - 347
  • [3] KENT TA, 1997, J CEREB BLOOD FLOW S, V17, pS14
  • [4] DYNAMIC MAGNETIC-RESONANCE-IMAGING OF HUMAN BRAIN ACTIVITY DURING PRIMARY SENSORY STIMULATION
    KWONG, KK
    BELLIVEAU, JW
    CHESLER, DA
    GOLDBERG, IE
    WEISSKOFF, RM
    PONCELET, BP
    KENNEDY, DN
    HOPPEL, BE
    COHEN, MS
    TURNER, R
    CHENG, HM
    BRADY, TJ
    ROSEN, BR
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (12) : 5675 - 5679
  • [5] Cerebral [O-15]water clearance in humans determined by PET .1. Theory and normal values
    Ohta, S
    Meyer, E
    Fujita, H
    Reutens, DC
    Evans, A
    Gjedde, A
    [J]. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 1996, 16 (05) : 765 - 780
  • [6] Absolute cerebral blood flow and blood volume measured by magnetic resonance imaging bolus tracking: Comparison with positron emission tomography values
    Ostergaard, L
    Smith, DF
    Vestergaard-Poulsen, P
    Hansen, SB
    Gee, AD
    Gjedde, A
    Gyldensted, C
    [J]. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 1998, 18 (04) : 425 - 432
  • [7] High resolution measurement of cerebral blood flow using intravascular tracer bolus passages .2. Experimental comparison and preliminary results.
    Ostergaard, L
    Sorensen, AG
    Kwong, KK
    Weisskoff, RM
    Gyldensted, C
    Rosen, BR
    [J]. MAGNETIC RESONANCE IN MEDICINE, 1996, 36 (05) : 726 - 736
  • [8] High resolution measurement of cerebral blood flow using intravascular tracer bolus passages .1. Mathematical approach and statistical analysis
    Ostergaard, L
    Weisskoff, RM
    Chesler, DA
    Gyldensted, C
    Rosen, BR
    [J]. MAGNETIC RESONANCE IN MEDICINE, 1996, 36 (05) : 715 - 725
  • [9] Porkka L.M., 1991, P SOC MAGN RES MED 1, P120
  • [10] QUANTIFICATION OF REGIONAL CEREBRAL BLOOD-FLOW AND VOLUME WITH DYNAMIC SUSCEPTIBILITY CONTRAST-ENHANCED MR-IMAGING
    REMPP, KA
    BRIX, G
    WENZ, F
    BECKER, CR
    GUCKEL, F
    LORENZ, WJ
    [J]. RADIOLOGY, 1994, 193 (03) : 637 - 641