Molecular Profiling: Moving Away from Tumor Philately

被引:54
作者
Reis-Filho, Jorge S. [1 ]
Weigelt, Britta [2 ]
Fumagalli, Debora [3 ]
Sotiriou, Christos [3 ]
机构
[1] Inst Canc Res, Mol Pathol Lab, Breakthrough Breast Canc Res Ctr, London SW3 6JB, England
[2] London Res Inst, Signal Transduct Lab, Canc Res UK, London WC2A 3PX, England
[3] Univ Libre Brussels, Breast Canc Translat Res Lab, Inst Jules Bordet, B-1000 Brussels, Belgium
关键词
GENE-EXPRESSION PROFILES; BREAST-CANCER; NEOADJUVANT CHEMOTHERAPY; PROGNOSIS; SUBTYPES; METASTASIS; PREDICTORS; CARCINOMAS; SIGNATURES; TAMOXIFEN;
D O I
10.1126/scitranslmed.3001329
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Despite the remarkable enhancements in breast cancer classification and characterization, an exhaustive comprehension of the underlying carcinogenic processes and an accurate prediction of its clinical behavior are yet to be achieved. On the wave of recent scientific advances and clinical findings, new cutting-edge technologies are poised to deliver an array of diverse molecular data that are expected to dramatically alter breast cancer diagnosis and treatment.
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页数:5
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