Multi-anode detection in electrospray ionization time-of-flight mass spectrometry

被引：16

作者：

Barbacci, DC

Russell, DH ^{[1
]}

Schultz, JA

Holocek, J

Ulrich, S

Burton, W

Van Stipdonk, M

机构：

[1] Texas A&M Univ, Dept Chem, Lab Biol Mass Spectrometry, College Stn, TX 77843 USA

[2] IonWerks Inc, Houston, TX USA

来源：

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY | 1998年 / 9卷 / 12期

关键词：

D O I：

10.1016/S1044-0305(98)00113-5

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

An electrospray ionization ion source coupled to a time-of-night mass analyzer incorporating a multi-anode time-to-digital converter is described. High-speed data acquisition (kHz mass spectral acquisition) rates are achieved. The four-anode detector produces a significant increase in detection/counting efficiency over that for a single-anode detector. In this work a 2.5 times increase in detection efficiency is demonstrated. The multi-anode detector is also used as a diagnostic tool to optimize transmission of the ion optics. (C) 1998 American Society for Mass Spectrometry.

引用

页码：1328 / 1333

页数：6

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