Infections in multiple myeloma

被引:17
作者
Paradisi, F [1 ]
Corti, G [1 ]
Cinelli, R [1 ]
机构
[1] Univ Florence, Sch Med, Clin Infect Dis, Careggi Hosp, I-50134 Florence, Italy
关键词
D O I
10.1016/S0891-5520(05)70151-3
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Multiple myeloma is a relatively rare but severe hematologic malignancy. Marked depression in production of normal immunoglobulins, mild neutropenia, and alkylant/steroid therapy or BMT/SCT all produce major suppression of the immune system in the totality of patients. Recurrent bacterial, fungal, and viral infections are an important cause of morbidity and the most common cause of death in these subjects. Prompt diagnosis and appropriate anti-infective chemotherapy are essential in order to reduce the risk of mortality.
引用
收藏
页码:373 / +
页数:14
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