Effects of L-carnitine on thyroid hormone metabolism and on physical exercise tolerance

被引：19

作者：

Benvenga, S

机构：

[1] Univ Messina, Sch Med, Sez Endocrinol, Dipartimento Clin Sperimentale Med & Farmacol, I-98125 Messina, Italy

[2] Univ Policlin Gaetano Martino, Programma Endocrinol Mol Clin, Azienda Osped, I-98125 Messina, Italy

来源：

HORMONE AND METABOLIC RESEARCH | 2005年 / 37卷 / 09期

关键词：

L-carnitine; nutrients; sports; physical exercise; thyroid hormone modulators;

D O I：

10.1055/s-2005-870424

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

L-carnitine (CARN) is a water-soluble, naturally occurring quaternary amine ubiquitous in biological fluids and animal tissues; in these tissues, CARN plays an important role in energy metabolism. Skeletal muscles store about 95% of a total of 20 g CARN contained in the adult human body, but high-intensity physical exercise decreases the CARN muscle content. The daily allowance of CARN is mainly satisfied by diet. Keeping in mind important interstudy differences, the general conclusion is that CARN supplementation may enhance athletic performance when coupled to physical exercise itself. Healthy, essentially sedentary persons and untrained individuals do not benefit from supplementation, and certainly not if CARN is administered for a few days. CARN was also shown to modulate thyroid hormone action in peripheral tissues, the most frequent modulation observed being inhibition.

引用

页码：566 / 571

页数：6

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