Implications of X-linked gene regulation for sex differences in disease pathogenesis (comment on DOI 10.1002/bies.201100047)

被引:5
作者
Klein, Sabra L. [1 ]
机构
[1] Johns Hopkins Bloomberg Sch Publ Hlth, W Harry Feinstone Dept Mol Microbiol & Immunol, Baltimore, MD USA
关键词
MICRORNAS; IMMUNITY;
D O I
10.1002/bies.201100128
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:789 / 790
页数:2
相关论文
共 8 条
[1]   Sex bias in neuroscience and biomedical research [J].
Beery, Annaliese K. ;
Zucker, Irving .
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS, 2011, 35 (03) :565-572
[2]   Sex Disparities in Cancer Mortality and Survival [J].
Cook, Michael B. ;
McGlynn, Katherine A. ;
Devesa, Susan S. ;
Freedman, Neal D. ;
Anderson, William F. .
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 2011, 20 (08) :1629-1637
[3]   Suppression of LPS-induced Interferon-γ and nitric oxide in splenic lymphocytes by select estrogen-regulated microRNAs: a novel mechanism of immune modulation [J].
Dai, Rujuan ;
Phillips, Rebecca A. ;
Zhang, Yan ;
Khan, Deena ;
Crasta, Oswald ;
Ahmed, S. Ansar .
BLOOD, 2008, 112 (12) :4591-4597
[4]   The X-files in immunity: sex-based differences predispose immune responses [J].
Fish, Eleanor N. .
NATURE REVIEWS IMMUNOLOGY, 2008, 8 (09) :737-744
[5]  
Klein SL, 2010, SEX HORMONES AND IMMUNITY TO INFECTION, P1, DOI 10.1007/978-3-642-02155-8
[6]   X-chromosome-located microRNAs in immunity: Might they explain male/female differences? The X chromosome-genomic context may affect X-located miRNAs and downstream signaling, thereby contributing to the enhanced immune response of females [J].
Pinheiro, Iris ;
Dejager, Lien ;
Libert, Claude .
BIOESSAYS, 2011, 33 (11) :791-802
[7]   Elevated 17β-Estradiol Protects Females from Influenza A Virus Pathogenesis by Suppressing Inflammatory Responses [J].
Robinson, Dionne P. ;
Lorenzo, Maria E. ;
Jian, William ;
Klein, Sabra L. .
PLOS PATHOGENS, 2011, 7 (07)
[8]   Sex differences in autoimmune diseases [J].
Voskuhl R. .
Biology of Sex Differences, 2 (1)