A radical tandem reaction with homolytic cleavage of a Ti-O bond

被引：106

作者：

Gansäuer, A

Rinker, B

Pierobon, M

Grimme, S

Gerenkamp, M

Mück-Lichtenfeld, C

机构：

[1] Univ Bonn, Kekule Inst Organ Chem & Biochem, D-53127 Bonn, Germany

[2] Univ Munster, Inst Organ Chem, D-49149 Munster, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2003年 / 42卷 / 31期

关键词：

epoxides; homolytic substitution; radical reactions; tandem reactions; titanium;

D O I：

10.1002/anie.200351240

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A radical merry-go-round. An electron is transferred from a titanocene(III) complex to the substrate and finally back to the catalyst in a novel atom-economical tandem reaction. Complex structures can be readily accessed (see scheme). The unprecedented mechanism involving a homolytic cleavage of a Ti-O bond is supported by DFT calculations.

引用

页码：3687 / 3690

页数：4

共 35 条

[1]

[Anonymous], 2001, Radicals in Organic Syntheses

[2] A new strategy for the synthesis of cyclic terpenoids based on the radical opening of acyclic epoxypolyenes [J].