Cognitive function and cerebral assessment in patients who have Cushing's syndrome

被引：47

作者：

Bourdeau, I

Bard, C

Forget, H

Boulanger, Y

Cohen, H

Lacroix, A

机构：

[1] Univ Montreal, Div Endocrinol, Dept Med, Hotel Dieu,Ctr Hosp, Montreal, PQ H2W 1T8, Canada

[2] Univ Montreal, Dept Radiol, Ctr Hosp, Hotel Dieu, Montreal, PQ H2W 1T8, Canada

[3] Univ Quebec, Dept Psychol, Hull, PQ J8X 3X7, Canada

[4] Univ Montreal, Dept Radiol, Hop St Luc, Cent Hosp, Montreal, PQ H2X 3J4, Canada

[5] Univ Quebec, Cognit Neurosci Ctr, Montreal, PQ H3C 3P8, Canada

来源：

ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA | 2005年 / 34卷 / 02期

关键词：

D O I：

10.1016/j.ecl.2005.01.016

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Cushing's syndrome (CS) is a relevant model to better understand the effects of glucocorticoid (GC) excess on the human brain. The importance of GC excess on the central nervous system is highlighted by the high prevalence of neuropsychiatric disorders such as depression and cognitive impairment in patients who have CS. In addition, there is a high incidence of apparent diffuse loss of brain volume in patients who have CS. Recent studies indicate at least partial reversibility of these abnormalities following correction of hypercortisolism.

引用

页码：357 / +

页数：14

共 60 条

[1] RESORPTION OF PERITUMOURAL EDEMA IN CEREBRAL GLIOMAS DURING DEXAMETHASONE TREATMENT EVALUATED BY NMR RELAXATION-TIME IMAGING [J].