HLA-peptide tetrameric complexes

被引：93

作者：

Ogg, GS ^{[1
]}

McMichael, AJ ^{[1
]}

机构：

[1] John Radcliffe Hosp, Nuffield Dept Med, Inst Mol Med, Oxford OX3 9DS, England

来源：

CURRENT OPINION IN IMMUNOLOGY | 1998年 / 10卷 / 04期

关键词：

D O I：

10.1016/S0952-7915(98)80110-6

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

HLA-peptide tetrameric complexes allow the direct ex vivo visualisation of antigen-specific CD8(+) T cells and natural killer cells by flow cytometry. Quantitation, phenotypic analysis and isolation of tetramer-binding cells has considerably extended our understanding of cytotoxic T lymphocyte and natural killer cell function.

引用

页码：393 / 396

页数：4

共 17 条

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