Protein regulation: Tag wrestling with relatives of ubiquitin

被引:33
作者
Hodges, M [1 ]
Tissot, C [1 ]
Freemont, PS [1 ]
机构
[1] Imperial Canc Res Fund, Mol Struct & Funct Lab, London WC2A 3PX, England
关键词
D O I
10.1016/S0960-9822(07)00477-0
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Ubiquitin modification is a well established way of regulating protein levels and activities. Modification by related ubiquitin-like proteins is turning out to have a diverse range of interesting cellular functions.
引用
收藏
页码:R749 / R752
页数:4
相关论文
共 25 条
[1]   The NF-kappa B and I kappa B proteins: New discoveries and insights [J].
Baldwin, AS .
ANNUAL REVIEW OF IMMUNOLOGY, 1996, 14 :649-683
[2]  
Boddy MN, 1996, ONCOGENE, V13, P971
[3]   The ubiquitin-proteasome pathway: The complexity and myriad functions of proteins death [J].
Ciechanover, A ;
Schwartz, AL .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (06) :2727-2730
[4]   SUMO-1 modification of IκBα inhibits NF-κB activation [J].
Desterro, JMP ;
Rodriguez, MS ;
Hay, RT .
MOLECULAR CELL, 1998, 2 (02) :233-239
[5]   Ubch9 conjugates SUMO but not ubiquitin [J].
Desterro, JMP ;
Thomson, J ;
Hay, RT .
FEBS LETTERS, 1997, 417 (03) :297-300
[6]   The disruption of ND10 during herpes simplex virus infection correlates with the Vmw11O- and proteasome-dependent loss of several PML isoforms [J].
Everett, RD ;
Freemont, P ;
Saitoh, H ;
Dasso, M ;
Orr, A ;
Kathoria, M ;
Parkinson, J .
JOURNAL OF VIROLOGY, 1998, 72 (08) :6581-6591
[7]   Ubiquitin-dependent protein degradation [J].
Hochstrasser, M .
ANNUAL REVIEW OF GENETICS, 1996, 30 :405-439
[8]   Structure, organization, and dynamics of promyelocytic leukemia protein nuclear bodies [J].
Hodges, M ;
Tissot, C ;
Howe, K ;
Grimwade, D ;
Freemont, PS .
AMERICAN JOURNAL OF HUMAN GENETICS, 1998, 63 (02) :297-304
[9]   Ubc9p is the conjugating enzyme for the ubiquitin-like protein Smt3p [J].
Johnson, ES ;
Blobel, G .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (43) :26799-26802
[10]   The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer [J].
Johnson, ES ;
Schwienhorst, I ;
Dohmen, RJ ;
Blobel, G .
EMBO JOURNAL, 1997, 16 (18) :5509-5519