Rocking the foundations of solid tumor growth by attacking the tumor's blood supply

被引:40
作者
Molema, G
Griffioen, AW
机构
[1] Groningen Utrecht Inst Drug Explorat, Dept Clin Immunol, Sect Tumor Immunol, NL-9713 GZ Groningen, Netherlands
[2] Groningen Utrecht Inst Drug Explorat, Dept Pharmacokinet & Drug Delivery, NL-9713 GZ Groningen, Netherlands
[3] Univ Hosp Maastricht, Dept Internal Med, Tumor Angiogenesis Lab, NL-6202 AZ Maastricht, Netherlands
来源
IMMUNOLOGY TODAY | 1998年 / 19卷 / 09期
关键词
D O I
10.1016/S0167-5699(98)01314-0
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Deprivation of tumor vascularization is a promising way to prevent tumor outgrowth. Various approaches are under investigation to achieve this, ranging from inhibition of endothelial cell growth or migration to selective tumor vascular targeting of chemotherapeutics. The rapid progress in the field of angiogenesis research, including results presented at a recent meeting*, is discussed here.
引用
收藏
页码:392 / 394
页数:3
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