Recombinant LH in ovarian stimulation

被引：20

作者：

Caglar, GS

Asimakopoulos, B

Nikolettos, N

Diedrich, K

Al-Hasani, S ^{[1
]}

机构：

[1] Med Univ Lubeck, Dept Obstet & Gynecol, D-23538 Lubeck, Germany

[2] Univ Democritus, Physiol Lab, Alexandroupolis, Greece

来源：

REPRODUCTIVE BIOMEDICINE ONLINE | 2005年 / 10卷 / 06期

关键词：

assisted reproduction technologies; folliculogenesis; LH supplementation; ovarian stimulation; recombinant luteinizing hormone;

D O I：

10.1016/S1472-6483(10)61123-6

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The advent of recombinant gonadotrophins brought significant changes in fertility therapy. Treatment options with recombinant gonadotrophins add more to knowledge on folliculogenesis and ovarian steroidogenesis. Over a decade, recombinant LH (rLH) has been used for clinical trials, and the amount of peripheral LH that is necessary for optimal follicular growth, oocyte maturation, subsequent embryo development and assisted reproduction outcome during ovulation induction can now be better evaluated. This review evaluates the effect of rLH supplementation on ovarian stimulation and assisted reproduction outcome. The studies conducted with rLH supplementation in ovarian stimulation in different groups of patients and in cases of controlled ovarian stimulation are clearly discussed in this review.

引用

收藏

页码：774 / 785

页数：12

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