Carbon nanotube fibers are compatible with mammalian cells and neurons

被引:45
作者
Dubin, Robert A. [3 ]
Callegari, Gerardo C. [2 ,3 ]
Kohn, Joachim
Neimark, Alexander V. [1 ]
机构
[1] Rutgers State Univ, Dept Chem & Biochem Engn, Piscataway, NJ 08854 USA
[2] TRI Princeton, Ctr Modeling & Characterizat Nanoporous Mat, Princeton, NJ 08542 USA
[3] Rutgers State Univ, New Jersey Ctr Biomat, Piscataway, NJ 08854 USA
关键词
biocompatibility; carbon nanotubes; cell adhesion; neurons;
D O I
10.1109/TNB.2008.2000144
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
We demonstrate the biocompatibility of carbon nanotube fibers (CNFs) fabricated from single-wall carbon nanotubes. Produced by a particle-coagulation spinning process, CNFs are "hair-like" conductive microwires, which uniquely combine properties of porous nanostructured scaffolds, high-area electrodes, and permeable microfluidic conduits. We report that CNFs are nontoxic and support the attachment, spreading, and growth of mammalian cells and the extension of processes from neurons in vitro. Our findings suggest that CNF may be employed for an electrical interfacing of nerve cells and external devices.
引用
收藏
页码:11 / 14
页数:4
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