学术探索
学术期刊
新闻热点
数据分析
智能评审

Nontraditional risk factors for cardiovascular disease in diabetes

被引：123
作者：
Fonseca, V
Desouza, C
Asnani, S
Jialal, I
机构：
[1] Tulane Univ, Med Ctr, Dept Med, Sect Endocrinol,Tulane Diabet Program, New Orleans, LA 70112 USA
[2] Univ Calif Davis, Lab Atherosclerosis & Metab Res, Sacramento, CA 95817 USA
来源：
ENDOCRINE REVIEWS | 2004年 / 25卷 / 01期
关键词：
D O I：
10.1210/er.2002-0034
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
People with type 2 diabetes are disproportionately affected by cardiovascular disease (CVD), compared with those without diabetes. Traditional risk factors do not fully explain this excess risk, and other "nontraditional" risk factors may be important. This review will highlight the importance of nontraditional risk factors for CVD in the setting of type 2 diabetes and discuss their role in the pathogenesis of the excess CVD morbidity and mortality in these patients. We will also discuss the impact of various therapies used in patients with diabetes on nontraditional risk factors.
引用
收藏
页码：153 / 175
页数：23
相关论文
共 265 条
  • [1] Relationship of generalized and regional adiposity to insulin sensitivity in men with NIDDM
    Abate, N
    Garg, A
    Peshock, RM
    StrayGundersen, J
    AdamsHuet, B
    Grundy, SM
    [J]. DIABETES, 1996, 45 (12) : 1684 - 1693
  • [2] UKPDS 59: Hyperglycemia and other potentially modifiable risk factors for peripheral vascular disease in type 2 diabetes
    Adler, AI
    Stevens, RJ
    Neil, A
    Stratton, IM
    Boulton, AJM
    Holman, RR
    [J]. DIABETES CARE, 2002, 25 (05) : 894 - 899
  • [3] AGEWALL S, 1995, J HYPERTENS, V13, P463
  • [4] Long-term follow-up of patients with mild coronary artery disease and endothelial dysfunction
    Al Suwaidi, J
    Hamasaki, S
    Higano, ST
    Nishimura, RA
    Holmes, DR
    Lerman, A
    [J]. CIRCULATION, 2000, 101 (09) : 948 - 954
  • [5] Insulin inhibits the pro-inflammatory transcription factor early growth response gene-1 (Egr)-1 expression in mononuclear cells (MNC) and reduces plasma tissue factor (TF) and plasminogen activator inhibitor-1 (PAI-1) concentrations
    Aljada, A
    Ghanim, H
    Mohanty, P
    Kapur, N
    Dandona, P
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2002, 87 (03) : 1419 - 1422
  • [6] Effect of insulin on human aortic endothelial nitric oxide synthase
    Aljada, A
    Dandona, P
    [J]. METABOLISM-CLINICAL AND EXPERIMENTAL, 2000, 49 (02): : 147 - 150
  • [7] Tumor necrosis factor-α inhibits insulin-induced increase in endothelial nitric oxide synthase and reduces insulin receptor content and phosphorylation in human aortic endothelial cells
    Aljada, A
    Ghanim, H
    Assian, E
    Dandona, P
    [J]. METABOLISM-CLINICAL AND EXPERIMENTAL, 2002, 51 (04): : 487 - 491
  • [8] Nuclear factor-κB suppressive and inhibitor-κB stimulatory effects of troglitazone in obese patients with type 2 diabetes:: Evidence of an antiinflammatory action?
    Aljada, A
    Garg, R
    Ghanim, H
    Mohanty, P
    Hamouda, W
    Assian, E
    Dandona, P
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2001, 86 (07) : 3250 - 3256
  • [9] Relationship of metabolic syndrome and fibrinolytic dysfunction to cardiovascular disease
    Anand, SS
    Yi, QL
    Gerstein, H
    Lonn, E
    Jacobs, R
    Vuksan, V
    Teo, K
    Davis, B
    Montague, P
    Yusuf, S
    [J]. CIRCULATION, 2003, 108 (04) : 420 - 425
  • [10] Effects of improved glycaemic control on endothelial function in patients with type 2 diabetes
    Bagg, W
    Whalley, GA
    Gamble, G
    Drury, PL
    Sharpe, N
    Braatvedt, GD
    [J]. INTERNAL MEDICINE JOURNAL, 2001, 31 (06) : 322 - 328
12345678910