Cotransplantation of umbilical cord MSCs to enhance engraftment of hematopoietic stem cells in patients with severe aplastic anemia

被引:41
作者
Chao, Y-H [1 ,2 ]
Tsai, C. [3 ]
Peng, C-T [4 ,5 ,6 ]
Wu, H-P [7 ,8 ]
Chan, C-K [9 ,10 ]
Weng, T. [4 ,5 ]
Wu, K-H [4 ,5 ,11 ]
机构
[1] Chung Shan Med Univ Hosp, Dept Pediat, Taichung, Taiwan
[2] Chung Shan Med Univ, Sch Med, Taichung, Taiwan
[3] Bionet Corp, Taipei, Taiwan
[4] China Med Univ & Hosp, Childrens Hosp, Dept Pediat, Taichung, Taiwan
[5] China Med Univ & Hosp, Sch Chinese Med, Taichung, Taiwan
[6] Asia Univ, Dept Biotechnol & Bioinformat, Taichung, Taiwan
[7] Buddhist Tzu Chi Gen Hosp, Taichung Branch, Dept Pediat, Taichung, Taiwan
[8] Natl Yang Ming Univ, Inst Clin Med, Taipei 112, Taiwan
[9] Chang Gung Univ, Grad Inst Clin Med Sci, Tao Yuan, Taiwan
[10] Taoyuan Gen Hosp, Dept Pediat, Tao Yuan, Taiwan
[11] China Med Univ Hosp, Dept Med Res, Stem Cell Res Lab, Taichung, Taiwan
关键词
TRANSPLANTATION; CULTURES; BLOOD;
D O I
10.1038/bmt.2010.305
中图分类号
Q6 [生物物理学];
学科分类号
071011 [生物物理学];
摘要
引用
收藏
页码:1391 / 1392
页数:2
相关论文
共 10 条
[1]
Cotransplantation of ex vivo-expanded mesenchymal stem cells accelerates lymphocyte recovery and may reduce the risk of graft failure in haploidentical hematopoietic stem-cell transplantation [J].
Ball, Lynne M. ;
Bernardo, Maria Ester ;
Roelofs, Helene ;
Lankester, Arjan ;
Cometa, Angela ;
Egeler, R. Maarten ;
Locatelli, Franco ;
Fibbe, Willem E. .
BLOOD, 2007, 110 (07) :2764-2767
[2]
Poor potential of proliferation and differentiation in bone marrow mesenchymal stem cells derived from children with severe aplastic anemia [J].
Chao, Yu-Hua ;
Peng, Ching-Tien ;
Harn, Horng-Jyh ;
Chan, Chin-Kan ;
Wu, Kang-Hsi .
ANNALS OF HEMATOLOGY, 2010, 89 (07) :715-723
[3]
Umbilical cord mesenchymal stem cells: Adjuvants for human cell transplantation [J].
Friedman, Robb ;
Betancur, Monica ;
Boissel, Laurent ;
Tuncer, Hande ;
Cetrulo, Curtis ;
Klingemann, Hans .
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2007, 13 (12) :1477-1486
[4]
APLASTIC-ANEMIA - ANALYSIS OF STROMAL CELL-FUNCTION IN LONG-TERM MARROW CULTURES [J].
HOLMBERG, LA ;
SEIDEL, K ;
LEISENRING, W ;
TOROKSTORB, B .
BLOOD, 1994, 84 (11) :3685-3690
[5]
Mesenchymal stem cells inhibit and stimulate mixed lymphocyte cultures and mitogenic responses independently of the major histocompatibility complex [J].
Le Blanc, K ;
Tammik, L ;
Sundberg, B ;
Haynesworth, SE ;
Ringdén, O .
SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 2003, 57 (01) :11-20
[6]
Transplantation of ex-vivo culture-expanded parental haploidentical mesenchymal stem cells to promote engraftment in pediatric recipients of unrelated donor umbilical cord blood: results of a phase I-II clinical trial [J].
MacMillan, M. L. ;
Blazer, B. R. ;
DeFor, T. E. ;
Wagner, J. E. .
BONE MARROW TRANSPLANTATION, 2009, 43 (06) :447-454
[7]
MSC for the improvement of hematopoietic engraftment [J].
Resnick, I. ;
Stepensky, P. ;
Elkin, G. ;
Barkatz, C. ;
Gurevich, O. ;
Prigozhina, T. ;
Pikarsky, E. ;
Waldman, E. ;
Amar, A. ;
Samuel, S. ;
Shapira, M. ;
Weintraub, M. ;
Or, R. .
BONE MARROW TRANSPLANTATION, 2010, 45 (03) :605-606
[8]
Multipotent stem cells from umbilical cord:: Cord is richer than blood! [J].
Secco, Mariane ;
Zucconi, Eder ;
Vieira, Natassia M. ;
Fogaca, Luciana L. Q. ;
Cerqueira, Antonia ;
Carvalho, Maria Denise F. ;
Jazedje, Tatiana ;
Okamoto, Oswaldo K. ;
Muotri, Alysson R. ;
Zatz, Mayana .
STEM CELLS, 2008, 26 (01) :146-150
[9]
VERFAILLIE CM, 1992, BLOOD, V79, P2821
[10]
Mesenchymal stem cells in the Wharton's jelly of the human umbilical cord [J].
Wang, HS ;
Hung, SC ;
Peng, ST ;
Huang, CC ;
Wei, HM ;
Guo, YJ ;
Fu, YS ;
Lai, MC ;
Chen, CC .
STEM CELLS, 2004, 22 (07) :1330-1337