Severe Acute Respiratory Syndrome Historical, Epidemiologic, and Clinical Features

被引：318

作者：

Hui, David S. C. ^{[1
]}

Zumla, Alimuddin ^{[2
]}

机构：

[1] Chinese Univ Hong Kong, Stanley Ho Ctr Emerging Infect Dis, Dept Med & Therapeut, Shatin, Hong Kong, Peoples R China

[2] UCL, Ctr Clin Microbiol, Royal Free Campus,2nd Floor,Rowland Hill St, London NW3 2PF, England

来源：

INFECTIOUS DISEASE CLINICS OF NORTH AMERICA | 2019年 / 33卷 / 04期

基金：

欧盟地平线“2020”;

关键词：

SARS; Coronavirus; Epidemic; Epidemiology; Clinical; Prevention; SARS CORONAVIRUS RNA; FUNCTIONAL RECEPTOR; CONVALESCENT PLASMA; DISEASE SEVERITY; GENOME SEQUENCE; CELL RESPONSES; LUNG PATHOLOGY; DNA VACCINE; VIRAL LOAD; HONG-KONG;

D O I：

10.1016/j.idc.2019.07.001

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Severe acute respiratory syndrome coronavirus (SARS-CoV), emerged from China and rapidly spread worldwide. Over 8098 people fell ill and 774 died before the epidemic ended in July 2003. Bats are likely an important reservoir for SARS-CoV. SARS-like CoVs have been detected in horseshoe bats and civet cats. The main mode of transmission of SARS-CoV is through inhalation of respiratory droplets. Faeco-oral transmission has been recorded. Strict infection control procedures with respiratory and contact precautions are essential. Fever and respiratory symptoms predominate, and diarrhea is common. Treatment involves supportive care. There are no specific antiviral treatments or vaccines available.

引用

页码：869 / +

页数：22

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