Bacterial subversion of lipid rafts

被引:90
作者
Lafont, F [1 ]
Abrami, L [1 ]
van der Goot, FG [1 ]
机构
[1] Univ Geneva, Dept Genet & Microbiol, CH-1211 Geneva 4, Switzerland
关键词
D O I
10.1016/j.mib.2003.12.007
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Bacteria rely on numerous basic cellular functions of their target cells to reach successful infection. The recent discovery that the plasma membrane contains specialized microdomains, called lipid rafts, with many specific functions but in particular with the ability to concentrate signaling molecules, has therefore attracted the attention of cellular microbiologists. Since then an increasing number of bacteria and their products have been shown to interact with lipid rafts to promote infection or intoxication. Here we review why certain bacteria and/or their products are attracted toward these lipid microdomains.
引用
收藏
页码:4 / 10
页数:7
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