Serratia marcescens nosocomial outbreak due to contamination of hexetidine solution

被引：38

作者：

Bosi, C

DavinRegli, A

Charrel, R

Rocca, B

Monnet, D

Bollet, C

机构：

[1] HYG & EPIDEMIOL HOSP,BACTERIOL LAB,MARSEILLE,FRANCE

[2] HOP SUD,SERV NEUROCHIRURG,MARSEILLE,FRANCE

[3] CTR HOSP LYON SUD,CTR COORDINAT LUTTE INFECT NOSOCOMIALES SUD EST,LYON,FRANCE

来源：

JOURNAL OF HOSPITAL INFECTION | 1996年 / 33卷 / 03期

关键词：

Serratia marcescens; RAPD typing; hexetidine disinfectant antiseptic; epidemiological marker; nosocomial infection;

D O I：

10.1016/S0195-6701(96)90005-5

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

During a 10-week period, 16 patients in a neurosurgery intensive care unit were involved in an outbreak of Serratia marcescens. The epidemic strain was found in several flasks of 1:4 diluted hexetidine solution, an antiseptic used for patient mouth washing. Testing of the bactericidal activity of the diluted antiseptic revealed that all the epidemic strains were able to grow in the diluted antiseptic solution. Strains isolated from clinical samples and from the antiseptic solution were compared by random amplification of polymorphic DNA. Epidemiologic typing data implicated the diluted antiseptic solution as the single source of this S. marcescens outbreak.

引用

页码：217 / 224

页数：8

共 19 条

[1] SERRATIA-MARCESCENS CONTAMINATION OF ANTISEPTIC SOAP CONTAINING TRICLOSAN - IMPLICATIONS FOR NOSOCOMIAL INFECTION [J].