The yeast Mediator complex and its regulation

被引：155

作者：

Björklund, S ^{[1
]}

Gustafsson, CM

机构：

[1] Umea Univ, Dept Med Biochem, S-90187 Umea, Sweden

[2] Karolinska Inst, Dept Med Nutr, S-14186 Huddinge, Sweden

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 2005年 / 30卷 / 05期

关键词：

D O I：

10.1016/j.tibs.2005.03.008

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The Mediator complex acts as a bridge, conveying regulatory information from enhancers and other control elements to the basal RNA polymerase II transcription machinery. Mediator is required for the regulated transcription of nearly all RNA polymerase II-dependent genes in Saccharomyces cerevisiae, and post-translational modifications of specific Mediator subunits can affect global patterns of gene transcription.

引用

页码：240 / 244

页数：5

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