Flow cytometry and T-cell response monitoring after smallpox vaccination

被引：8

作者：

Poccia, F ^{[1
]}

Gioia, C ^{[1
]}

Montesano, C ^{[1
]}

Martini, F ^{[1
]}

Horejsh, D ^{[1
]}

Castilletti, C ^{[1
]}

Pucillo, LP ^{[1
]}

Capobianchi, MR ^{[1
]}

Ippolito, G ^{[1
]}

机构：

[1] Natl Inst Infect Dis Lazzaro Spallanzani, IRCCS, I-00149 Rome, Italy

来源：

EMERGING INFECTIOUS DISEASES | 2003年 / 9卷 / 11期

关键词：

D O I：

10.3201/eid0911.030349

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Orthopoxvirus zoonosis or smallpox as result of bioterrorism or biological warfare represents a risk for epidemic spread. By monitoring T-cell responses by flow cytometry, we observed a recall response after recent vaccination against smallpox. When the high similarity between the orthopoxviruses is considered, this rapid assay that uses vaccinia antigens could identify recently exposures.

引用

页码：1468 / 1470

页数：3

共 15 条

[1] Computer-based design of an HLA-haplotype and HIV-clade independent cytotoxic T-lymphocyte (CTL) assay for monitoring HIV-specific immunity
Amicosante, M
Gioia, C
Montesano, C
Casetti, R
Topino, S
D'Offizi, G
Cappelli, G
Ippolito, G
Colizzi, V
Poccia, F
Pucillo, LP
[J]. MOLECULAR MEDICINE, 2002, 8 (12) : 798 - 807
[2] Monitoring HIV-specific CD8+T cell responses by intracellular cytokine production
Betts, MR
Casazza, JP
Koup, RA
[J]. IMMUNOLOGY LETTERS, 2001, 79 (1-2) : 117 - 125
[3] Expansion of pre-terminally differentiated CD8 T cells in chronic HIV-positive patients presenting a rapid viral rebound during structured treatment interruption
D'Offizi, G
Montesano, C
Agrati, C
Gioia, C
Amicosante, M
Topino, S
Narciso, P
Pucillo, LP
Ippolito, G
Poccia, F
[J]. AIDS, 2002, 16 (18) : 2431 - 2438
[4] The loss of CMV-Specific CD27-T-Cell effectors in a patient with recurrences of CMV retinitis is independent of HIV-1 viremia
D'Offizi, G
Ciapparoni, V
Gioia, C
Goletti, D
Agrati, C
Pucillo, LP
Narciso, P
Poccia, F
[J]. INFECTION, 2002, 30 (05) : 323 - 325
[5] Human cytotoxic T-cell memory: Long-lived responses to vaccinia virus
Demkowicz, WE
Littaua, RA
Wang, JM
Ennis, FA
[J]. JOURNAL OF VIROLOGY, 1996, 70 (04) : 2627 - 2631
[6] VACCINIA VIRUS-SPECIFIC CD8+ CYTOTOXIC LYMPHOCYTES-T IN HUMANS
DEMKOWICZ, WE
ENNIS, FA
[J]. JOURNAL OF VIROLOGY, 1993, 67 (03) : 1538 - 1544
[7] Effector CD4(+) and CD8(+) T-cell mechanisms in the control of respiratory virus infections
Doherty, PC
Topham, DJ
Tripp, RA
Cardin, RD
Brooks, JW
Stevenson, PG
[J]. IMMUNOLOGICAL REVIEWS, 1997, 159 : 105 - 117
[8] Primary induction of human CD8+ cytotoxic T lymphocytes and interferon-γ-producing T cells after smallpox vaccination
Ennis, FA
Cruz, J
Demkowicz, WE
Rothman, AL
McClain, DJ
[J]. JOURNAL OF INFECTIOUS DISEASES, 2002, 185 (11) : 1657 - 1659
[9] Dose-related effects of smallpox vaccine
Frey, SE
Newman, FK
Cruz, J
Shelton, WB
Tennant, JM
Polach, T
Rothman, AL
Kennedy, JS
Wolff, M
Belshe, RB
Ennis, FA
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 2002, 346 (17) : 1275 - 1280
[10] Functionally inert HIV-specific cytotoxic T lymphocytes do not play a major role in chronically infected adults and children
Goulder, PJR
Tang, YH
Brander, C
Betts, MR
Altfeld, M
Annamalai, K
Trocha, A
He, SQ
Rosenberg, ES
Ogg, G
O'Callaghan, CA
Kalams, SA
McKinney, RE
Mayer, K
Koup, RA
Pelton, SI
Burchett, SK
McIntosh, K
Walker, BD
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 2000, 192 (12) : 1819 - 1831

← 1 2 →