Three new isoflavone glycosides from Tongmai granules

被引：12

作者：

Wang, Fu-Rong ^{[1
]}

Yang, Xiu-Wei ^{[1
]}

Zhang, Ying ^{[2
]}

Liu, Jian-Xun ^{[2
]}

Yang, Xin-Bao ^{[2
,3
]}

Liu, Yang ^{[3
]}

Shi, Ren-Bing ^{[3
]}

机构：

[1] Peking Univ, Sch Pharmaceut Sci, Dept Nat Med, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China

[2] China Acad Chinese Med Sci, Xiyuan Hosp, Res Ctr, Beijing 100091, Peoples R China

[3] Beijing Univ Chinese Med, Beijing 100029, Peoples R China

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2011年 / 13卷 / 04期

关键词：

Tongmai granules; 3'-methoxydaidzein-7; 4'-di-O--d-glucopyranoside; biochanin A-8-C--d-apiofuranosyl-(16)-O--d-glucopyranoside; daidzein-7-O--d-glucopyranosyl-(14)-O--d-glucopyranoside; DPPH radical-scavenging activity; PUERARIA-LOBATA; OFFICINALIS;

D O I：

10.1080/10286020.2011.556090

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

Three new isoflavone glycosides, 3'-methoxydaidzein-7,4'-di-O--d-glucopyranoside (1), biochanin A-8-C--d-apiofuranosyl-(16)-O--d-glucopyranoside (2), daidzein-7-O--d-glucopyranosyl-(14)-O--d-glucopyranoside (3), and a new natural isoflavone glycoside, daidzein-7-O--d-glucopyranosyl-(14)-O--d-glucopyranoside (4) were isolated along with 18 known isoflavones from the EtOAc and n-BuOH fractions of the aqueous extraction of Tongmai granules. All the isoflavones were obtained and determined for the first time from Tongmai granules. The structures of these compounds were elucidated by spectral methods. It was confirmed that the compounds 1-4 were originally from Puerariae Lobatae Radix based on HPLC-DAD analysis of the crude drug extract. The isoflavones isolated were tested for their antioxidative activities by measuring the capacities of scavenging the 2,2'-diphenyl-1-picrylhydrazyl radical.

引用

页码：319 / 329

页数：11

共 13 条

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