Infantile botulism caused by Clostridium butyricum type E toxin

被引：29

作者：

Abe, Yuichi ^{[1
]}

Negasawa, Tetsuro ^{[1
]}

Monma, Chie ^{[2
]}

Oka, Akira ^{[1
]}

机构：

[1] Natl Ctr Child Hlth & Dev, Div Child Neurol, Tokyo 1578504, Japan

[2] Tokyo Metropolitan Inst Publ Hlth, Dept Microbiol, Div Food Microbiol, Tokyo, Japan

来源：

PEDIATRIC NEUROLOGY | 2008年 / 38卷 / 01期

关键词：

D O I：

10.1016/j.pediatrneurol.2007.08.013

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The case of a 9-month-old boy with infantile botulism caused by Clostridium butyricum type E toxin is reported. Because infantile botulism is rare in Japan, it was difficult to diagnose it at an early stage. Electrophysiologic findings were useful for the diagnosis, and were characterized by incremental responses (waxing) to short intervals and rapid repetitive nerve stimulation. A bioassay for botulism in mice indicated that the patient had botulism due to type E or F botulinum toxin. C butyricum type E was isolated from his feces, confirming the diagnosis. This is the first known case of infantile botulism due to C butyricum type E toxin in Japan. (C) 2008 by Elsevier Inc. All rights reserved.

引用

页码：55 / 57

页数：3

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