Isolation and Analysis of Bioactive Constituents of Sour Cherry (Prunus cerasus) Seed Kernel: An Emerging Functional Food

被引:46
作者
Bak, Istvan [1 ]
Lekli, Istvan [1 ]
Juhasz, Bela [1 ]
Varga, Edit [1 ]
Varga, Balazs [1 ]
Gesztelyi, Rudolf [1 ]
Szendrei, Levente [1 ]
Tosaki, Arpad [1 ]
机构
[1] Univ Debrecen, Dept Pharmacol, Fac Pharm, Med & Hlth Sci Ctr, H-4032 Debrecen, Hungary
关键词
flavonoids; free radicals; sour cherry kernel; unsaturated fatty acids; vitamin E; PROANTHOCYANIDINS;
D O I
10.1089/jmf.2009.0188
中图分类号
R914 [药物化学];
学科分类号
100705 [微生物与生化药学];
摘要
A plant-based diet reduces the risk for the development of several chronic diseases, such as ischemic heart disease or cancer due to natural compounds found in plants. Numerous cereals, berries, fruits, and vegetables, including sour cherry (Prunus cerasus), which is a favored fruit worldwide, contain biological active components. The antioxidant components of the sour cherry seed kernel have not been investigated until now. The aim of our study was to isolate and analyze the bioactive constituents of sour cherry seed kernel. We separated the oil fraction of the kernel; then the remaining solid fraction was dried, and the oil-free kernel extract was further analyzed. Our results show that sour cherry seed kernel oil contains vegetable oils including unsaturated fatty acids, oleic acids, alpha-tocopherol, tocotrienols, and tocopherol-like components. The components of the solid fraction include various bioactive structures such as polyphenols, flavonoids, vegetable acids, and pro- and anthocyanidins, which could have useful therapeutic effects in the prevention of various vascular diseases.
引用
收藏
页码:905 / 910
页数:6
相关论文
共 24 条
[1]
Cardioprotective mechanisms of Prunus cerasus (sour cherry) seed extract against ischemia-reperfusion-induced damage in isolated rat hearts [J].
Bak, Istvan ;
Lekli, Istvan ;
Juhasz, Bela ;
Nagy, Norbert ;
Varga, Edit ;
Varadi, Judit ;
Gesztelyi, Rudolf ;
Szabo, Gergo ;
Szendrei, Levente ;
Bacskay, Ildiko ;
Vecsernyes, Miklos ;
Antal, Miklos ;
Fesus, Laszlo ;
Boucher, Francois ;
de Leiris, Joel ;
Tosaki, Arpad .
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2006, 291 (03) :H1329-H1336
[2]
Cakiner-Egilmez Tulay, 2008, Insight, V33, P20
[3]
Cui JH, 2002, J CARDIOVASC PHARM, V40, P760
[4]
RETRACTED: Cardioprotection with palm tocotrienol: antioxidant activity of tocotrienol is linked with its ability to stabilize proteasomes (Retracted Article) [J].
Das, S ;
Powell, SR ;
Wang, P ;
Divald, A ;
Nesaretnam, K ;
Tosaki, A ;
Cordis, GA ;
Maulik, N ;
Das, DK .
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2005, 289 (01) :H361-H367
[5]
Omega 3 - Omega 6: What is right for the liver? [J].
El-Badry, Ashraf Mohammad ;
Graf, Rolf ;
Clavien, Pierre-Alain .
JOURNAL OF HEPATOLOGY, 2007, 47 (05) :718-725
[6]
Ghosh D, 2007, ASIA PAC J CLIN NUTR, V16, P200
[7]
Dietary supplements and functional foods: 2 sides of a coin? [J].
Halsted, CH .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2003, 77 (04) :1001S-1007S
[8]
A systematic screening of total antioxidants in dietary plants [J].
Halvorsen, BL ;
Holte, K ;
Myhrstad, MCW ;
Barikmo, I ;
Hvattum, E ;
Remberg, SF ;
Wold, AB ;
Haffner, K ;
Baugerod, H ;
Andersen, LF ;
Moskaug, JO ;
Jacobs, DR ;
Blomhoff, R .
JOURNAL OF NUTRITION, 2002, 132 (03) :461-471
[9]
Sweet and sour cherry phenolics and their protective effects on neuronal cells [J].
Kim, DO ;
Heo, HJ ;
Kim, YJ ;
Yang, HS ;
Lee, CY .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2005, 53 (26) :9921-9927
[10]
Dietary guidelines for healthy American adults - A statement for health professionals from the Nutrition Committee, American Heart Association [J].
Krauss, RM ;
Deckelbaum, RJ ;
Ernst, N ;
Fisher, E ;
Howard, BV ;
Knopp, RH ;
Kotchen, T ;
Lichtenstein, AH ;
McGill, HC ;
Pearson, TA ;
Prewitt, TE ;
Stone, NJ ;
VanHorn, L ;
Weinberg, R .
CIRCULATION, 1996, 94 (07) :1795-1800