Exploring the potential energy surface of retinal, a comparison of the performance of different methods

被引：17

作者：

Blomgren, F ^{[1
]}

Larsson, S ^{[1
]}

机构：

[1] Chalmers Univ Technol, Dept Chem & Biosci, SE-41296 Gothenburg, Sweden

来源：

JOURNAL OF COMPUTATIONAL CHEMISTRY | 2005年 / 26卷 / 07期

关键词：

retinal; potential energy surface;

D O I：

10.1002/jcc.20210

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The ground state structure of retinal has been investigated. We found that DFT and CASSCF produce different results for the bond length alternation in a model system of retinal. Quantum mechanics/molecular mechanics calculations including the closest surrounding amino acids have been performed, using DFT and CASSCF to calculate the structure of retinal in the protein cavity. The planarity of the retinal molecule is affected by the surrounding protein. DFT and CASSCF produce different twist angles. The difference between CASSCF and DFT appears to be related to the positively charged nitrogen of the Schiff base, which leads to different pi-bond orders produced by the two methods. (c) 2005 Wiley Periodicals, Inc.

引用

页码：738 / 742

页数：5

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