Oral clopidogrel load in aspirin-resistant Capsular warning syndrome

被引：37

作者：

Fahey, CD ^{[1
]}

Alberts, MJ ^{[1
]}

Bernstein, RA ^{[1
]}

机构：

[1] Northwestern Univ, Feinberg Sch Med, Ken & Ruth Davee Dept Neurol & Clin Neurol Sci, Stroke Program, Chicago, IL 60611 USA

来源：

NEUROCRITICAL CARE | 2005年 / 2卷 / 02期

关键词：

ischemic stroke; antiplatelet therapy; transient ischemic attack; acute brain ischemia; Capsular warning syndrome;

D O I：

10.1385/NCC:2:2:183

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Introduction: Capsular warning syndrome (CWS) carries a significant risk of permanent stroke. There are no proven therapies for preventing completed stroke in this unstable situation. Methods: Clinical observation in two patients with aspirin-resistant CWS treated with a loading dose of oral clopidogrel. Results: Both patients had excellent neurological outcome, although one sustained an asymptomatic brain infarction. Conclusion: High-dose oral clopidogrel plus aspirin merits formal evaluation in high-risk transient brain ischemia such as CWS, preferably in a randomized trial compared to aspirin alone.

引用

页码：183 / 184

页数：2

共 14 条

[1] No evidence for microembolism in clustering transient ischemic attacks [J].