Bisepoxides as biselectrophiles in the silicon-induced domino synthesis of highly functionalized carbocycles

被引：22

作者：

Bräuer, N ^{[1
]}

Dreessen, S ^{[1
]}

Schaumann, E ^{[1
]}

机构：

[1] Tech Univ Clausthal, Inst Organ Chem, D-38678 Clausthal Zellerfeld, Germany

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 15期

关键词：

D O I：

10.1016/S0040-4039(99)00386-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of silylated thioacetals 2a, b with different bisepoxides 1, 4, 5 is investigated. The silicon-induced domino reaction opens a short route from D-mannitol to the highly functionalized carbocycles 7-10. Using this cascade, 4-epi-validatol (12) is synthesized. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：2921 / 2924

页数：4

共 10 条

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