Newly appreciated therapeutic effect of GLP-1 receptor agonists: Reduction in postprandial lipemia

被引：9

作者：

Bandsma, Robert H. J.

Lewis, Gary F.

机构：

[1] Univ Toronto, Dept Med, Toronto, ON M5G 2C4, Canada

[2] Univ Toronto, Dept Physiol, Toronto, ON M5G 2C4, Canada

来源：

ATHEROSCLEROSIS | 2010年 / 212卷 / 01期

关键词：

GLUCAGON-LIKE PEPTIDE-1; FATTY-ACIDS; INSULIN; GLUCOSE; EXENATIDE; SECRETION; HUMANS;

D O I：

10.1016/j.atherosclerosis.2010.06.033

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：40 / 41

页数：2

共 15 条

[1] Intestinal lipoprotein overproduction in insulin-resistant states [J].

Adeli, Khosrow ;

Lewis, Gary F. .

CURRENT OPINION IN LIPIDOLOGY, 2008, 19 (03) :221-228

[2]

DeFronzo RA, 2008, CURR MED RES OPIN, V24, P2943, DOI [10.1185/03007990802418851, 10.1185/03007990802418851 ]

[3] The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes [J].

Drucker, Daniel J. ;

Nauck, Michael A. .

LANCET, 2006, 368 (9548) :1696-1705

[4] The biology of incretin hormones [J].

Drucker, DJ .

CELL METABOLISM, 2006, 3 (03) :153-165

[5] The glucagon-like peptide 1 receptor is essential for postprandial lipoprotein synthesis and secretion in hamsters and mice [J].

Hsieh, J. ;

Longuet, C. ;

Baker, C. L. ;

Qin, B. ;

Federico, L. M. ;

Drucker, D. J. ;

Adeli, K. .

DIABETOLOGIA, 2010, 53 (03) :552-561

[6]

Lewis G F, 1995, J Atheroscler Thromb, V2 Suppl 1, pS34

[7] Vildagliptin therapy reduces postprandial intestinal triglyceride-rich lipoprotein particles in patients with type 2 diabetes [J].

Matikainen, N. ;

Manttari, S. ;

Schweizer, A. ;

Ulvestad, A. ;

Mills, D. ;

Dunning, B. E. ;

Foley, J. E. ;

Taskinen, M. -R. .

DIABETOLOGIA, 2006, 49 (09) :2049-2057

[8] Glucagon-like peptide 1 abolishes the postprandial rise in triglyceride concentrations and lowers levels of non-esterified fatty acids in humans [J].

Meier, JJ ;

Gethmann, A ;

Götze, O ;

Gallwitz, B ;

Holst, JJ ;

Schmidt, WE ;

Nauck, MA .

DIABETOLOGIA, 2006, 49 (03) :452-458

[9] Normalization of glucose concentrations and deceleration of gastric emptying after solid meals during intravenous glucagon-like peptide 1 in patients with type 2 diabetes [J].

Meier, JJ ;

Gallwitz, B ;

Salmen, S ;

Goetze, O ;

Holst, JJ ;

Schmidt, WE ;

Nauck, MA .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2003, 88 (06) :2719-2725

[10] CNTO736, a Novel Glucagon-Like Peptide-1 Receptor Agonist, Ameliorates Insulin Resistance and Inhibits Very Low-Density Lipoprotein Production in High-Fat-Fed Mice [J].

Parlevliet, Edwin T. ;

Elst, Janny P. Schroeder-van der ;

Corssmit, Eleonora P. M. ;

Picha, Kristen ;

O'Neil, Karyn ;

Stojanovic-Susulic, Vedrana ;

Ort, Tatiana ;

Havekes, Louis M. ;

Romijn, Johannes A. ;

Pijl, Hanno .

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2009, 328 (01) :240-248

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