The differences of femoral neck geometric parameters: effects of age, gender and race

被引:35
作者
Zhang, F. [1 ]
Tan, L. -J. [1 ]
Lei, S. -F. [1 ,3 ,4 ]
Deng, H. -W. [1 ,2 ,3 ,4 ]
机构
[1] Hunan Normal Univ, Lab Mol & Stat Genet, Coll Life Sci, Changsha 410081, Hunan, Peoples R China
[2] Shanghai Univ Sci & Technol, Ctr Systemat Biomed Res, Shanghai 201800, Peoples R China
[3] Univ Missouri, Dept Orthoped Surg, Kansas City, MO 64108 USA
[4] Univ Missouri, Dept Basic Med Sci, Kansas City, MO 64108 USA
关键词
Age; Femoral neck geometric parameters; Race; Sex; BONE-MINERAL DENSITY; QUANTITATIVE COMPUTED-TOMOGRAPHY; HIP FRACTURE INCIDENCE; X-RAY ABSORPTIOMETRY; LIFE-STYLE FACTORS; BIOMECHANICAL BASIS; OSTEOPOROTIC FRACTURES; POSTMENOPAUSAL WOMEN; SEXUAL-DIMORPHISM; HUMAN PEDIGREES;
D O I
10.1007/s00198-009-1057-0
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
This study aims at investigating the effects of age, sex, and ethnicity on five femoral neck geometric parameters (FNGPs): femoral neck periosteal diameter, cross-sectional area, cortical thickness, sectional modulus, and buckling ratio and found that the three factors would influence the FNGPs. Bone geometry is one of the most important predictors of bone strength and osteoporotic fractures. This study aims at investigating the effects of age, sex, and ethnicity on five femoral neck geometric parameters (FNGPs): femoral neck periosteal diameter (W), cross-sectional area (CSA), cortical thickness (CT), sectional modulus (Z), and buckling ratio (BR). In the studied 861 Caucasian subjects and 3,021 Chinese individuals, CSA, CT, and Z displayed trends of decrease with age, but W and BR showed increasing trends with age in both Chinese and Caucasian females and males (p < 0.05). W, CSA, CT, and Z were significantly higher (p a parts per thousand currency signaEuro parts per thousand 0.001) in Caucasians than in Chinese and higher in males than in females except for BR between Chinese males and Chinese females. In conclusion, the differences of FNGPs according to gender and ethnicity provide important implications in the different prevalence of osteoporotic fracture among different gender and ethnic groups.
引用
收藏
页码:1205 / 1214
页数:10
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