Bradyrhizobium japonicum FixK2, a crucial distributor in the FixLJ-dependent regulatory cascade for control of genes inducible by low oxygen levels

被引:96
作者
Nellen-Anthamatten, D [1 ]
Rossi, P [1 ]
Preisig, O [1 ]
Kullik, I [1 ]
Babst, M [1 ]
Fischer, HM [1 ]
Hennecke, H [1 ]
机构
[1] Swiss Fed Inst Technol, Inst Mikrobiol, CH-8092 Zurich, Switzerland
关键词
D O I
10.1128/JB.180.19.5251-5255.1998
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Bradyrhizobium japonicum possesses a second fixK-like gene, fixK(2), in addition to the previously identified fixK(1) gene, The expression of both genes depends in a hierarchical fashion on the low-oxygen-responsive two-component regulatory system FixLJ, whereby FixJ first activates fixK(2), whose product then activates fixK(1). While the target genes for control by FixK(1) are unknown, there is evidence for activation of the fixNOQP, fixGHIS, and rpoN(1) genes and some heme biosynthesis and nitrate respiration genes by FixK(2), FixK(2) also regulates its own structural gene, directly or indirectly, in a negative way.
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收藏
页码:5251 / 5255
页数:5
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