Functional connectivity patterns of human magnetoencephalographic recordings: a 'small-world' network?

被引：412

作者：

Stam, CJ ^{[1
]}

机构：

[1] Vrije Univ Amsterdam, Ctr Med, Dept Clin Neurophysiol, NL-1007 MB Amsterdam, Netherlands

来源：

NEUROSCIENCE LETTERS | 2004年 / 355卷 / 1-2期

关键词：

magnetoencephalography; synchronization; functional connectivity; gamma; graph theory; small-world network; information processing;

D O I：

10.1016/j.neulet.2003.10.063

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

EEG and MEG (magnetoencephalography) are widely used to study functional connectivity between different brain regions. We address the question whether such connectivity patterns display an optimal organization for information processing. MEG recordings of five healthy human subjects were converted to sparsely connected graphs (N = 126; k = 15) by applying a suitable threshold to the N * N matrix of synchronization strengths. For intermediate frequencies 18 - 30 Hz) the synchronization patterns were similar to those of an ordered graph with a consistent drop of synchronization strength as a function of distance. For low (< 8 Hz) and high (> 30 Hz) frequency bands the synchronization patterns displayed the features of a so-called 'small-world' network. This might reflect an optimal organization pattern for information processing, connecting any two brain area by only a small number of intermediate steps. (C) 2004 Elsevier Ireland Ltd. All rights reserved.

引用

页码：25 / 28

页数：4

共 19 条

[1] Emergence of scaling in random networks [J].

Barabási, AL ;

Albert, R .

SCIENCE, 1999, 286 (5439) :509-512

[2] Synchronization in small-world systems [J].

Barahona, M ;

Pecora, LM .

PHYSICAL REVIEW LETTERS, 2002, 89 (05) :054101/1-054101/4

[3] Gamma, alpha, delta, and theta oscillations govern cognitive processes [J].

Basar, E ;

Basar-Eroglu, C ;

Karakas, S ;

Schürmann, M .

INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY, 2001, 39 (2-3) :241-248

[4] Functional connectivity of gamma EEG activity is modulated at low frequency during conscious recollection [J].

Burgess, AP ;

Ali, L .

INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY, 2002, 46 (02) :91-100

[5] Scale-free networks are ultrasmall [J].

Cohen, R ;

Havlin, S .

PHYSICAL REVIEW LETTERS, 2003, 90 (05) :4

[6] Dynamic imaging of coherent sources:: Studying neural interactions in the human brain [J].

Gross, J ;

Kujala, J ;

Hämäläinen, M ;

Timmermann, L ;

Schnitzler, A ;

Salmelin, R .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (02) :694-699

[7] The large-scale organization of metabolic networks [J].

Jeong, H ;

Tombor, B ;

Albert, R ;

Oltvai, ZN ;

Barabási, AL .

NATURE, 2000, 407 (6804) :651-654

[8] Fast response and temporal coherent oscillations in small-world networks [J].

Lago-Fernández, LF ;

Huerta, R ;

Corbacho, F ;

Sigüenza, JA .

PHYSICAL REVIEW LETTERS, 2000, 84 (12) :2758-2761

[9] Synchronization between prefrontal and posterior association cortex during human working memory [J].

Sarnthein, J ;

Petsche, H ;

Rappelsberger, P ;

Shaw, GL ;

von Stein, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (12) :7092-7096

[10] Phase-coupling of theta-gamma EEG rhythms during short-term memory processing [J].

Schack, B ;

Vath, N ;

Petsche, H ;

Geissler, HG ;

Möller, E .

INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY, 2002, 44 (02) :143-163

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