Functional relationship between Escherichia coli RNase E and the CafA protein

被引：63

作者：

Wachi, M

Umitsuki, G

Nagai, K

机构：

[1] Department of Bioengineering, Tokyo Institute of Technology, Midori-ku, Yokohama 226

来源：

MOLECULAR & GENERAL GENETICS | 1997年 / 253卷 / 04期

关键词：

RNase E; rne; ams; cafA; Escherichia coli;

D O I：

10.1007/s004380050352

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We analyzed the functional relationship between the Escherichia coli RNase E and the CafA protein, which show extensive sequence similarity. The temperature-sensitive growth of the RNase E mutant strain ams1 was partially suppressed by multicopy plasmids bearing the cafA gene. Introduction of a cafA::cat mutation enhanced the temperature sensitivity of the ams1 mutant. These results suggest that there is a functional homology between these two proteins.

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页码：515 / 519

页数：5

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