The metabolic syndrome: a cause of sexual dysfunction in women

被引：81

作者：

Esposito, K

Ciotola, M

Marfella, R

Di Tommaso, D

Cobellis, L

Giugliano, D

机构：

[1] Univ Naples 2, Dept Geriatr & Metab Dis, I-80138 Naples, Italy

[2] Univ Naples 2, Dept Gynecol Obstet & Reprod, I-80138 Naples, Italy

来源：

INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH | 2005年 / 17卷 / 03期

关键词：

metabolic syndrome; female sexual dysfunction; inflammation; PCR;

D O I：

10.1038/sj.ijir.3901310

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

Female sexual dysfunction (FSD) is a significant public health problem. We assessed the prevalence of FSD in premenopausal women with the metabolic syndrome as compared to the general female population. Compared with the control group ( N = 80), women with the metabolic syndrome ( N = 120) had reduced mean full Female Sexual Function Index (FSFI) score (23.2 +/- 5.4 vs 30.1 +/- 4.7, P<0.001), reduced satisfaction rate (3.5 +/- 1.1 vs 4.7 +/- 1.2, P<0.01), and higher circulating levels of C-reactive protein (CRP: 2.2 (0.6/4.9) vs 0.8 (0.2/2.9) mg/l, median (interquartile range), P = 0.01). There was an inverse relation between CRP levels and FSFI score ( r = - 0.32, P = 0.02). Investigation of female sexuality is suggested for patients with the metabolic syndrome.

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页码：224 / 226

页数：3

相关论文

共 11 条

[1]

Slimness is associated with greater intercourse and lesser masturbation frequency [J].

Brody, S .

JOURNAL OF SEX & MARITAL THERAPY, 2004, 30 (04) :251-261

[2]

The function of sildenafil on female sexual pathways: a double-blind, cross-over, placebo-controlled study [J].

Caruso, S ;

Intelisano, G ;

Farina, M ;

Di Mari, L ;

Agnello, C .

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 2003, 110 (02) :201-206

[3]

Nitrergic neurotransmission mediates the non-adrenergic non-cholinergic responses in the clitoral corpus cavernosum of the rabbit [J].

Cellek, S ;

Moncada, S .

BRITISH JOURNAL OF PHARMACOLOGY, 1998, 125 (08) :1627-1629

[4]

Executive summary of the Third Report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III) [J].

Cleeman, JI ;

Grundy, SM ;

Becker, D ;

Clark, LT ;

Cooper, RS ;

Denke, MA ;

Howard, WJ ;

Hunninghake, DB ;

Illingworth, DR ;

Luepker, RV ;

McBride, P ;

McKenney, JM ;

Pasternak, RC ;

Stone, NJ ;

Van Horn, L ;

Brewer, HB ;

Ernst, ND ;

Gordon, D ;

Levy, D ;

Rifkind, B ;

Rossouw, JE ;

Savage, P ;

Haffner, SM ;

Orloff, DG ;

Proschan, MA ;

Schwartz, JS ;

Sempos, CT ;

Shero, ST ;

Murray, EZ .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2001, 285 (19) :2486-2497

[5]

Prevalence and predictors of sexual dysfunction in patients with type 1 diabetes [J].

Enzlin, P ;

Mathieu, C ;

Van den Bruel, A ;

Vanderschueren, D ;

Demyttenaere, K .

DIABETES CARE, 2003, 26 (02) :409-414

[6]

Effect of lifestyle changes on erectile dysfunction in obese men - A randomized controlled trial [J].

Esposito, K ;

Giugliano, F ;

Di Palo, C ;

Giugliano, G ;

Marfella, R ;

D'Andrea, F ;

D'Armiento, M ;

Giugliano, D .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2004, 291 (24) :2978-2984

[7]

FELDMAN HA, 1994, INT J EPIDEMIOL, V29, P524

[8]

Role of the nitric oxide-cyclic GMP pathway in regulation of vaginal blood flow [J].

Kim, SW ;

Jeong, SJ ;

Munarriz, R ;

Kim, NN ;

Goldstein, I ;

Traish, AM .

INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH, 2003, 15 (05) :355-361

[9]

Sexual dysfunction in the United States - Prevalence and predictors [J].

Laumann, EO ;

Paik, A ;

Rosen, RC .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1999, 281 (06) :537-544

[10]

The Female Sexual Function Index (FSFI): A multidimensional self-report instrument for the assessment of female sexual function [J].

Rosen, R ;

Brown, C ;

Heiman, J ;

Leiblum, S ;

Meston, C ;

Shabsigh, R ;

Ferguson, D ;

D'Agostino, R .

JOURNAL OF SEX & MARITAL THERAPY, 2000, 26 (02) :191-208