Expression of oct-4 and c-kit antigens in endometriosis

被引：61

作者：

Pacchiarotti, Arianna ^{[1
]}

Caserta, Donatella ^{[1
]}

Sbracia, Marco ^{[2
]}

Moscarini, Massimo ^{[1
]}

机构：

[1] Univ Roma La Sapienza, I-00183 Rome, Italy

[2] Univ Roma Tor Vergata, Rome, Italy

来源：

FERTILITY AND STERILITY | 2011年 / 95卷 / 03期

关键词：

Endometriosis; stem cells; oct-4; c-kit; OVARIAN-CANCER; CELLS; POPULATION; MARKERS; TUMORS;

D O I：

10.1016/j.fertnstert.2010.10.029

中图分类号：

R71 [妇产科学];

学科分类号：

100211 [妇产科学];

摘要：

The objective of this study was to test the expression of the oct-4 and c-kit, both markers of stem cells, in the ectopic endometrial tissue of endometriotic lesions of women with severe endometriosis. Our findings show that ectopic epithelial cells express oct-4 and c-kit and this suggests that the ectopic endometrium in endometriosis has a stem cell origin and could explain the possible progression to ovarian cancer. (Fertil Steril (R) 2011;95:1171-3. (C) 2011 by American Society for Reproductive Medicine.)

引用

收藏

页码：1171 / 1173

页数：3

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