Epidemiology and risk factors of colorectal polyps

被引:195
作者
Oines, Mari [1 ,2 ,3 ]
Helsingen, Lise M. [1 ,2 ,3 ]
Bretthauer, Michael [1 ,2 ,3 ,4 ,5 ]
Emilsson, Louise [1 ,4 ,6 ]
机构
[1] Univ Oslo, Inst Hlth & Soc, Clin Effectiveness Res Grp, Oslo, Norway
[2] Oslo Univ Hosp, Dept Transplantat Med, Oslo, Norway
[3] Oslo Univ Hosp, KG Jebsen Ctr Colorectal Canc Res, Oslo, Norway
[4] Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA USA
[5] Frontier Sci Fdn, Boston, MA USA
[6] Vardcentralen Varmlands Nysater, Ctr Clin Res, Saffle, Varmland County, Sweden
关键词
Colonic polyps; Epidemiology; Risk factors; Adenomatous polyps; BODY-MASS INDEX; CIGARETTE-SMOKING; SERRATED POLYPS; POOLED ANALYSIS; COLON-CANCER; ALCOHOL-CONSUMPTION; ADENOMATOUS POLYPS; ADVANCED NEOPLASIA; PHYSICAL-ACTIVITY; RESISTANT STARCH;
D O I
10.1016/j.bpg.2017.06.004
中图分类号
R57 [消化系及腹部疾病];
学科分类号
100201 [内科学];
摘要
The lifetime risk of colorectal cancer (CRC) in the Western world is around 5%. CRC commonly develops from precursor lesions termed polyps, classified as adenomatous or serrated polyps according to growth pattern. Despite the well-known connection between polyps and cancer, most polyps will never develop into CRC. For those that do, the time until CRC development is generally thought of as >10 years. This gives opportunity for interventional strategies to prevent transformation into cancer. This article aims to provide an overview of the epidemiology of and risk factors for colorectal polyps in the average risk population, and will encompass the effect of age, gender, ethnicity, smoking, obesity, alcohol, physical activity, NSAIDs and dietary factors on colorectal polyps. (C) 2017 Elsevier Ltd. All rights reserved.
引用
收藏
页码:419 / 424
页数:6
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