EGEETomo:: a user-friendly, fault-tolerant and grid-enabled application for 3D reconstruction in electron tomography

被引:1
作者
Bilbao-Castro, J. R. [1 ]
Garcia, I. [1 ]
Fernandez, J. J. [1 ]
机构
[1] Univ Almeria, Dept Comp Architecture & Elect, Almeria 04120, Spain
关键词
D O I
10.1093/bioinformatics/btm459
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Electron tomography is the leading technique to elucidate the structure of complex biological specimens. Due to the resolution needs, huge reconstructions are required. Grid computing has the potential to face the significant computational demands involved. However, there are a number of key issues, such as stability or difficult user-grid interaction, that currently preclude fully exploitation of its potential. EGEETomo is a user-friendly application that facilitates the interaction with the grid for the non-specialized user and automates job submission and supervision. In addition, EGEETomo is supplied with an automated fault recovery mechanism, which is key to make all the work transparent to the user. EGEETomo significantly accelerates tomographic reconstruction by exploiting the computational resources in the EGEE grid with minimal user intervention.
引用
收藏
页码:3391 / 3393
页数:3
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