Prevention of Contrast-Induced Acute Kidney Injury: an Update

被引：88

作者：

Chalikias, George ^{[1
]}

Drosos, Ioannis ^{[2
]}

Tziakas, Dimitrios N. ^{[1
]}

机构：

[1] Democritus Univ Thrace, Univ Cardiol Dept, Sch Med, Dragana 68131, Alexandroupolis, Greece

[2] Univ Med Ctr Mainz, Ctr Cardiol, Cardiol 1, Mainz, Germany

来源：

CARDIOVASCULAR DRUGS AND THERAPY | 2016年 / 30卷 / 05期

关键词：

Contrast induced nephropathy; Acute kidney injury; Contrast media; Coronary angiography; Percutaneous coronary intervention; Prevention; RANDOMIZED CONTROLLED-TRIALS; MEDIUM-INDUCED NEPHROPATHY; HIGH-RISK PATIENTS; CORONARY-ANGIOGRAPHY; N-ACETYLCYSTEINE; SODIUM-BICARBONATE; RENAL-INSUFFICIENCY; ASCORBIC-ACID; CARDIAC-CATHETERIZATION; PERIPHERAL ANGIOGRAPHY;

D O I：

10.1007/s10557-016-6683-0

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

Contrast-induced acute kidney injury (CI-AKI) is a common complication of intravascular administration of contrast media used in coronary angiography, percutaneous coronary intervention and other diagnostic and interventional procedures. This review article aims at summarizing the published literature regarding the prevention of CI-AKI, by focusing on available high-quality meta-analyses addressing this matter. Apart from adequate hydration, a number of pharmacologic agents have been proposed as potential candidates to be included in the routine preparation, prior to the patient's arrival in the cardiac catheterization laboratory. Among them, statins and N-acetylcysteine appear to be the most extensively studied ones. Throughout this article we present the available data on CI-AKI prevention and provide a critical clinical appraisal, as well as a summary of currently available guidelines.

引用

页码：515 / 524

页数：10

共 82 条

[1]

Protective effect of apocynin, a NADPH-oxidase inhibitor, against contrast-induced nephropathy in the diabetic rats: A comparison with n-acetylcysteine [J].