Fish oil supplementation improves visual evoked potentials in children with phenylketonuria

被引：46

作者：

Beblo, S

Reinhardt, H

Muntau, AC

Mueller-Felber, W

Roscher, AA

Koletzko, B

机构：

[1] Univ Munich, Dr Von Haunerschen Kinderspital, DIv Metab Dis & Nutr, D-80337 Munich, Germany

[2] Univ Munich, Friedrich Baur Inst, Munich, Germany

来源：

NEUROLOGY | 2001年 / 57卷 / 08期

关键词：

D O I：

10.1212/WNL.57.8.1488

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Visual evoked potentials (VEP) were measured in 36 patients with early-treated phenylketonuria (PKU; aged 1 to 11 years) and good metabolic control before and after supplementation with omega-3 long-chain polyunsaturated fatty acids (LC-PUFA) from fish oil. Patients with PKU had significantly longer P100 latencies than 22 age-matched control subjects. After 3 months of LC-PUFA supplementation, VEP latencies improved significantly in PKU patients but did not change in 12 untreated healthy children. The authors conclude that omega-3 LC-PUFA are essential substrates for nervous system function even beyond infancy.

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页码：1488 / 1491

页数：4

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