Smoking cessation-related weight gain-beneficial effects on muscle mass, strength and bone health

被引:34
作者
Rom, Oren [1 ]
Reznick, Abraham Z. [1 ]
Keidar, Zohar [2 ]
Karkabi, Khaled [3 ]
Aizenbud, Dror [1 ,4 ]
机构
[1] Technion Israel Inst Technol, Dept Anat & Cell Biol, Rappaport Fac Med, Efron St,POB 9649, IL-31096 Haifa, Israel
[2] Rambam Hlth Care Campus, Dept Nucl Med, Haifa, Israel
[3] Technion Israel Inst Technol, Dept Family Med, Rappaport Fac Med, IL-31096 Haifa, Israel
[4] Rambam Hlth Care Campus, Dept Orthodont & Craniofacial Anomalies, Haifa, Israel
关键词
Body composition; bone mineral density; muscle strength; osteoporosis; sarcopenia; skeletal muscle; smoking cessation; PHYSICAL-ACTIVITY; MINERAL DENSITY; WOMEN; VALIDATION; SARCOPENIA; COTININE; RECEPTOR; MEN;
D O I
10.1111/add.12761
中图分类号
R194 [卫生标准、卫生检查、医药管理];
学科分类号
100404 [儿少卫生与妇幼保健学];
摘要
AimsTo examine the effects of smoking cessation on body composition and muscle strength in comparison with continued smoking. Design and SettingTwelve-month longitudinal study of adult smokers conducted in Haifa, Israel. ParticipantsEighty-one smokers recruited from a smoking cessation programme combining group counselling and varenicline treatment. MeasurementsMeasurements were taken at the beginning of the programme and after 12 months. Body composition was assessed by dual-energy X-ray absorptiometry. Muscle strength was measured by handgrip dynamometry and predicted one-repetition maximum tests. Dietary intake and physical activity levels were estimated using questionnaires. Smoking status was determined by urine cotinine. The effect of smoking cessation was assessed using univariate and multivariable linear regression analyses. FindingsForty-one participants (age 4412 years) completed all baseline and follow-up measurements (76% continued smokers; 24% quitters). All measures of body composition and muscle strength were increased among quitters when compared with continued smokers. Adjusted differences [95% confidence interval (CI)] between quitters and smokers were: body weight 4.43kg (1.56-7.31kg); lean mass 1.26kg (0.24-2.28kg); fat mass 3.15kg (0.91-5.39kg); bone mineral content 48.76g (12.06-85.54g); bone mineral density 0.024g/cm(2) (0.004-0.043g/cm(2)); handgrip strength 3.6kg (1.12-6.08kg); predicted one-repetition maximum of chest press 7.85kg (1.93-13.76kg); and predicted one-repetition maximum of leg press 17.02kg (7.29-26.75kg). Conclusions Smoking cessation is associated with weight gain mainly through accumulating extra fat, but is also associated with increased muscle mass, muscle strength and bone density.
引用
收藏
页码:326 / 335
页数:10
相关论文
共 43 条
[1]
Abramson Joseph H, 2011, Epidemiol Perspect Innov, V8, P1, DOI 10.1186/1742-5573-8-1
[2]
Weight gain in smokers after quitting cigarettes: meta-analysis [J].
Aubin, Henri-Jean ;
Farley, Amanda ;
Lycett, Deborah ;
Lahmek, Pierre ;
Aveyard, Paul .
BMJ-BRITISH MEDICAL JOURNAL, 2012, 345
[3]
NUTRITION EPIDEMIOLOGY - HOW DO WE KNOW WHAT THEY ATE [J].
BARRETTCONNOR, E .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 1991, 54 (01) :S182-S187
[4]
Validity and reproducibility of the Physical Activity Scale for the Elderly (PASE) questionnaire for the measurement of the physical activity level in patients after total knee arthroplasty [J].
Bolszak, Sylvain ;
Casartelli, Nicola C. ;
Impellizzeri, Franco M. ;
Maffiuletti, Nicola A. .
BMC MUSCULOSKELETAL DISORDERS, 2014, 15
[5]
The influence of smoking on vitamin D status and calcium metabolism [J].
Brot, C ;
Jorgensen, NR ;
Sorensen, OH .
EUROPEAN JOURNAL OF CLINICAL NUTRITION, 1999, 53 (12) :920-926
[6]
Brzyckis M., 1998, PRACTICAL APPROACH S
[7]
Alterations in Skeletal Muscle Cell Homeostasis in a Mouse Model of Cigarette Smoke Exposure [J].
Caron, Marc-Andre ;
Morissette, Mathieu C. ;
Theriault, Marie-Eve ;
Nikota, Jake K. ;
Staempfli, Martin R. ;
Debigare, Richard .
PLOS ONE, 2013, 8 (06)
[8]
Sarcopenia in elderly men and women - The Rancho Bernardo Study [J].
Castillo, EM ;
Goodman-Gruen, D ;
Kritz-Silverstein, D ;
Morton, DJ ;
Wingard, DL ;
Barrett-Connor, E .
AMERICAN JOURNAL OF PREVENTIVE MEDICINE, 2003, 25 (03) :226-231
[9]
Sarcopenia: European consensus on definition and diagnosis [J].
Cruz-Jentoft, Alfonso J. ;
Baeyens, Jean Pierre ;
Bauer, Juergen M. ;
Boirie, Yves ;
Cederholm, Tommy ;
Landi, Francesco ;
Martin, Finbarr C. ;
Michel, Jean-Pierre ;
Rolland, Yves ;
Schneider, Stephane M. ;
Topinkova, Eva ;
Vandewoude, Maurits ;
Zamboni, Mauro .
AGE AND AGEING, 2010, 39 (04) :412-423
[10]
CIGARETTE-SMOKING, STEROID-HORMONES, AND BONE-MINERAL DENSITY IN YOUNG-WOMEN [J].
DANIEL, M ;
MARTIN, AD ;
DRINKWATER, DT .
CALCIFIED TISSUE INTERNATIONAL, 1992, 50 (04) :300-305