Fusarium verticillioides abscess of the nasal septum in an immunosuppressed child:: Case report and identification of the morphologically atypical fungal strain

被引:31
作者
Dornbusch, HJ
Buzina, W
Summerbell, RC
Lass-Flörl, C
Lackner, H
Schwinger, W
Sovinz, P
Urban, C
机构
[1] Med Univ Graz, Inst Hyg, A-8010 Graz, Austria
[2] Med Univ Graz, Div Pediat Hematol Oncol, A-8010 Graz, Austria
[3] Med Univ Innsbruck, Inst Hyg & Social Med, Innsbruck, Austria
[4] Cent Bur Schimmelcultures, Utrecht, Netherlands
关键词
D O I
10.1128/JCM.43.4.1998-2001.2004
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Morphologically atypical Fusarium verticillioides causing a nasal abscess in a severely immunosuppressed child was successfully treated with repeated surgical intervention and liposomal amphotericin B, despite amphotericin B resistance in vitro. Definitive identification was achieved by sequencing the translation elongation factor alpha gene after ribosomal sequencing proved inadequate.
引用
收藏
页码:1998 / 2001
页数:4
相关论文
共 24 条
[1]   Fusariosis associated with pathogenic Fusarium species colonization of a hospital water system:: A new paradigm for the epidemiology of opportunistic mold infections [J].
Anaissie, EJ ;
Kuchar, RT ;
Rex, JH ;
Francesconi, A ;
Kasai, M ;
Müller, FMC ;
Lozano-Chiu, M ;
Summerbell, RC ;
Dignani, MC ;
Chanock, SJ ;
Walsh, TJ .
CLINICAL INFECTIOUS DISEASES, 2001, 33 (11) :1871-1878
[2]   Fusarium, a significant emerging pathogen in patients with hematologic malignancy: Ten years' experience at a cancer center and implications for management [J].
Boutati, EI ;
Anaissie, EJ .
BLOOD, 1997, 90 (03) :999-1008
[3]   Fungal biodiversity - as found in nasal mucus [J].
Buzina, W ;
Braun, H ;
Freudenschuss, K ;
Lackner, A ;
Habermann, W ;
Stammberger, H .
MEDICAL MYCOLOGY, 2003, 41 (02) :149-161
[4]  
de Hoog G.S., 2000, ATLAS CLIN FUNGI, VSecond
[5]   Human fusariosis [J].
Dignani, MC ;
Anaissie, E .
CLINICAL MICROBIOLOGY AND INFECTION, 2004, 10 :67-75
[6]  
Domsch KH., 1993, Compendium of Soil Fungi volumes 1, V2
[7]   In vitro fungicidal activities of voriconazole, itraconazole, and amphotericin B against opportunistic moniliaceous and dematiaceous fungi [J].
Espinel-Ingroff, A .
JOURNAL OF CLINICAL MICROBIOLOGY, 2001, 39 (03) :954-958
[8]  
Gerlach W., 1982, Mitt Biol Bundesanst Land Forstwirtsch Berl Dahlem, V209, P1, DOI DOI 10.2307/3792677
[9]  
Guarro J, 2000, J CLIN MICROBIOL, V38, P419
[10]   MIXED INTRANASAL INFECTION CAUSED BY FUSARIUM-SOLANI AND A ZYGOMYCETE IN A LEUKEMIC PATIENT [J].
LOPES, JO ;
DEMELLO, ES ;
KLOCK, C .
MYCOSES, 1995, 38 (7-8) :281-284