Selection of cross-resistance following exposure of Pseudomonas aeruginosa clinical isolates to ciprofloxacin or cefepime

被引:12
作者
Alyaseen, SA
Piper, KE
Rouse, MS
Steckelberg, JM
Patel, R
机构
[1] Mayo Clin, Coll Med, Div Infect Dis, Dept Internal Med, Rochester, MN 55905 USA
[2] Mayo Clin, Coll Med, Div Clin Microbiol, Dept Lab Med & Pathol, Rochester, MN 55905 USA
关键词
D O I
10.1128/AAC.49.6.2543-2545.2005
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Exposure of ciprofloxacin- and cefepime-susceptible Pseudomonas aeruginosa isolates to increasing concentrations of ciprofloxacin selected for ciprofloxacin resistance in 26/27 and cefepime nonsusceptibility in 7/27 isolates. Exposure of the isolates to increasing concentrations of cefepime selected for cefepime nonsusceptibility in 20/27 isolates but not for ciprofloxacin resistance.
引用
收藏
页码:2543 / 2545
页数:3
相关论文
共 10 条
[1]   Type II topoisomerase mutations in fluoroquinolone-resistant clinical strains of Pseudomonas aeruginosa isolated in 1998 and 1999:: Role of target enzyme in mechanism of fluoroquinolone resistance [J].
Akasaka, T ;
Tanaka, M ;
Yamaguchi, A ;
Sato, K .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2001, 45 (08) :2263-2268
[2]  
[Anonymous], M07A6 NCCLS
[3]   Antibacterial spectrum of a novel des-fluoro(6) quinolone, BMS-284756 [J].
Fung-Tomc, JC ;
Minassian, B ;
Kolek, B ;
Huczko, E ;
Aleksunes, L ;
Stickle, T ;
Washo, T ;
Gradelski, E ;
Valera, L ;
Bonner, DP .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2000, 44 (12) :3351-3356
[4]  
Lee YS, 2000, ELEC SOC S, V2000, P182
[5]   A new member of the tripartite multidrug efflux pumps, MexVW-OprM, in Pseudomonas aeruginosa [J].
Li, Y ;
Mima, T ;
Komori, Y ;
Morita, Y ;
Kuroda, T ;
Mizushima, T ;
Tsuchiya, T .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2003, 52 (04) :572-575
[6]   Use of a genetic approach to evaluate the consequences of inhibition of efflux pumps in Pseudomonas aeruginosa [J].
Lomovskaya, O ;
Lee, A ;
Hoshino, K ;
Ishida, H ;
Mistry, A ;
Warren, MS ;
Boyer, E ;
Chamberland, S ;
Lee, VJ .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1999, 43 (06) :1340-1346
[7]   Assignment of the substrate-selective subunits of the MexEF-OprN multidrug efflux pump of Pseudomonas aeruginosa [J].
Maseda, H ;
Yoneyama, H ;
Nakae, T .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2000, 44 (03) :658-664
[8]   Acquisition of multidrug-resistant Pseudomonas aeruginosa in patients in intensive care units:: Role of antibiotics with antipseudomonal activity [J].
Paramythiotou, E ;
Lucet, JC ;
Timsit, JF ;
Vanjak, D ;
Paugam-Burtz, C ;
Trouillet, JL ;
Belloc, S ;
Kassis, N ;
Karabinis, A ;
Andremont, A .
CLINICAL INFECTIOUS DISEASES, 2004, 38 (05) :670-677
[9]   Determination of 16S rRNA sequences of enterococci and application to species identification of nonmotile Enterococcus gallinarum isolates [J].
Patel, R ;
Piper, KE ;
Rouse, MS ;
Steckelberg, JM ;
Uhl, JR ;
Kohner, P ;
Hopkins, MK ;
Cockerill, FR ;
Kline, BC .
JOURNAL OF CLINICAL MICROBIOLOGY, 1998, 36 (11) :3399-3407
[10]   Pseudomonas aeruginosa ventilator-associated pneumonia:: Comparison of episodes due to piperacillin-resistant versus piperacillin-susceptible organisms [J].
Trouillet, JL ;
Vuagnat, A ;
Combes, A ;
Kassis, N ;
Chastre, J ;
Gibert, C .
CLINICAL INFECTIOUS DISEASES, 2002, 34 (08) :1047-1054