Fe-HCl: An efficient reagent for deprotection of oximes as well as selective oxidative hydrolysis of nitroalkenes and nitroalkanes to ketones

被引：37

作者：

Pradhan, PK ^{[1
]}

Dey, S ^{[1
]}

Jaisankar, P ^{[1
]}

Giri, VS ^{[1
]}

机构：

[1] Indian Inst Chem Biol, Dept Med Chem, Kolkata 700032, W Bengal, India

来源：

SYNTHETIC COMMUNICATIONS | 2005年 / 35卷 / 07期

关键词：

deprotection of oximes; Fe; HCl; hydrolysis; ketones; nitroalkanes; nitroalkenes; oxidation;

D O I：

10.1081/SCC-200051681

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Fe-HCI mixture was found to selectively perform oxidative hydrolysis of the nitroalkenes 1a-j and nitroalkanes 2a-j to the ketones 3a-j. Also, the reagent was observed to deprotect the oximes 7a-j to carbonyl compounds 8a-j in excellent yields.

引用

页码：913 / 922

页数：10

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