Proline-catalysed asymmetric amination of α,α-disubstituted aldehydes:: synthesis of configurationally stable enantioenriched α-aminoaldehydes

被引：138

作者：

Vogt, H

Vanderheiden, S

Bräse, S

机构：

[1] Univ Karlsruhe, Inst Organ Chem, D-76131 Karlsruhe, Germany

[2] Univ Bonn, Kekule Inst Organ Chem & Biochem, D-53121 Bonn, Germany

来源：

CHEMICAL COMMUNICATIONS | 2003年 / 19期

关键词：

D O I：

10.1039/b305465a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Proline-catalysed amination of alpha,alpha-disubstituted racemic aldehydes with azodicarboxylates proceeds smoothly to give configurationally stable scalemic aldehydes and oxazolidinones in up to 86% ee.

引用

页码：2448 / 2449

页数：2

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