The contribution of vitamin C to healing of experimental fractures

被引：41

作者：

Yimaz, C

Erdemli, E

Selek, H

Kinik, H

Arikan, M

Erdemli, B

机构：

[1] Ankara Univ, Sch Med, Dept Orthoped & Traumatol, Ankara, Turkey

[2] Ankara Univ, Sch Med, Dept Histol & Embryol, Ankara, Turkey

来源：

ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY | 2001年 / 121卷 / 07期

关键词：

vitamin C; fracture healing; rat;

D O I：

10.1007/s004020100272

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

The benefits of various minerals and vitamins on fracture healing have been demonstrated in animal models. Vitamin C is an essential substance in fracture healing but has not been studied previously on an experimental basis. Sixteen rats were grouped randomly into control and vitamin C-supplemented groups. The right tibias of all rats were fractured by digital manipulation. One group received single high dose of vitamin C intramuscularly. On the 5th, 10th, 15th, and 20th days, two rats from each group were killed and the tibias examined under light microscopy. It was seen that the vitamin C-supplemented group went through the stages of fracture healing faster compared with the control group.

引用

页码：426 / 428

页数：3

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