Preparation of enamides via palladium-catalyzed amidation of enol tosylates

被引：176

作者：

Klapars, A ^{[1
]}

Campos, KR ^{[1
]}

Chen, CY ^{[1
]}

Volante, RP ^{[1
]}

机构：

[1] Merck Res Labs, Dept Proc Res, Rahway, NJ 07065 USA

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 06期

关键词：

D O I：

10.1021/ol050117y

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] A Pd-catalyzed coupling of enol tosylates and amides has been developed. Ligand screening revealed dipf as the most general ligand for this transformation. A variety of enol tosylates were coupled to an array of enamides in 58-97% yield.

引用

页码：1185 / 1188

页数：4

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