Successful treatment of antiepileptic drug hypersensitivity syndrome with intravenous immune globulin

被引:39
作者
Scheuerman, O
Nofech-Moses, Y
Rachmel, A
Ashkenazi, S [1 ]
机构
[1] Schneider Childrens Med Ctr Israel, Dept Pediat A, IL-49181 Petah Tiqwa, Israel
[2] Schneider Childrens Med Ctr Israel, Clin Pharmacol Unit, IL-49181 Petah Tiqwa, Israel
[3] Schneider Childrens Med Ctr Israel, Infect Dis Unit, IL-49181 Petah Tiqwa, Israel
[4] Tel Aviv Univ, Sackler Sch Med, IL-69978 Tel Aviv, Israel
关键词
antiepileptic drugs; hypersensitivity; immune globulin;
D O I
10.1542/peds.107.1.e14
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Intravenous immune globulin (IVIG) has proved beneficial for severe immunologically related cutaneous adverse reactions. We report a child with severe antiepileptic drug hypersensitivity syndrome who was successfully treated with IVIG. IVIG should be considered in the pharmacologic armamentarium of severe antiepileptic drug hypersensitivity syndrome.
引用
收藏
页码:art. no. / e14
页数:2
相关论文
共 10 条
[1]   Reversal of erythema multiforme major with cyclophosphamide and prednisone [J].
Eastham, JH ;
Segal, JL ;
Gomez, MF ;
Cole, GW .
ANNALS OF PHARMACOTHERAPY, 1996, 30 (06) :606-607
[2]   Acute management of hypersensitivity reactions and seizures [J].
Griebel, ML .
EPILEPSIA, 1998, 39 :S17-S21
[3]   Corticosteroid treatment of erythema multiforme major (Stevens-Johnson syndrome) in children [J].
Kakourou, T ;
Klontza, D ;
Soteropoulou, F ;
Kattamis, C .
EUROPEAN JOURNAL OF PEDIATRICS, 1997, 156 (02) :90-93
[4]   TREATMENT OF STEVENS-JOHNSON SYNDROME WITH POOLED HUMAN INTRAVENOUS IMMUNE GLOBULIN [J].
MOUDGIL, A ;
PORAT, S ;
BRUNNEL, P ;
JORDAN, SC .
CLINICAL PEDIATRICS, 1995, 34 (01) :48-51
[5]  
Phan T G, 1999, Australas J Dermatol, V40, P153, DOI 10.1046/j.1440-0960.1999.00347.x
[6]   DRUG-INDUCED TOXIC EPIDERMAL NECROLYSIS TREATED WITH CYCLOSPORINE [J].
RENFRO, L ;
GRANTKELS, JM ;
DAMAN, LA .
INTERNATIONAL JOURNAL OF DERMATOLOGY, 1989, 28 (07) :441-444
[7]   Use of intravenous immunoglobulin in the treatment of severe cutaneous drug reactions in patients with AIDS [J].
Sanwo, M ;
Nwadiuko, R ;
Beall, G .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1996, 98 (06) :1112-1115
[8]   Antiepileptic drug hypersensitivity syndrome [J].
Schlienger, RG ;
Shear, NH .
EPILEPSIA, 1998, 39 :S3-S7
[9]   ANTICONVULSANT HYPERSENSITIVITY SYNDROME - INVITRO ASSESSMENT OF RISK [J].
SHEAR, NH ;
SPIELBERG, SP .
JOURNAL OF CLINICAL INVESTIGATION, 1988, 82 (06) :1826-1832
[10]   Inhibition of toxic epidermal necrolysis by blockade of CD95 with human intravenous immunoglobulin [J].
Viard, I ;
Wehrli, P ;
Bullani, R ;
Schneider, P ;
Holler, N ;
Salomon, D ;
Hunziker, T ;
Saurat, JH ;
Tschopp, J ;
French, LE .
SCIENCE, 1998, 282 (5388) :490-493